Exploring phytochemicals of Withania somnifera from different vicinity for functional foods

Dhama, Pooja; Li, Yiyang; Sharma, Anita

doi:10.1016/j.jfutfo.2023.02.010

Cited by 5 publications

(2 citation statements)

References 37 publications

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“…MS, one of the most mainstream analytical techniques for components analysis, has been widely reported in many aspects of the food science and NPs discovery. Its flexibility, high selectivity, and lower detection limits, as well as its compatibility with diverse separation techniques such as gas chromatography (GC), liquid chromatography (LC), capillary electrophoresis (CE), and ion mobility (IM) make it an ideal instrument for FCs analysis applications [87][88][89] . To optimize of metabolite separation, MS is routinely coupled with other separation techniques depending on the polarity, ionization, and volatility of metabolites.…”

Section: Ms-based Discovery Strategy For Fcs and Nps Analysismentioning

confidence: 99%

The application and perspective of NMR and MS based strategies for functional compounds mining in medicinal and dietary plants

Zhang,

Li,

Liang

et al. 2024

Food Science and Human Wellness

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Medicinal and dietary plants provide numerous nutritional and functional compounds and also have various potential health benefits to humanity. The specific and efficient techniques for accurate identification of nutritional compounds and functional metabolites is crucial for the development of functional foods from medicinal and dietary plants. Nuclear magnetic resonance (NMR) and mass spectrometry (MS) are indispensable and essential technologies that provide an unsurpassed wealth of untargeted identification, quantitative and qualitative analysis, and structural information in the study of food and plant products. In the past decade, the rapid development of modern analytical technology has led to the emergence of new approaches and strategies for natural products discovery. Especially the application of novel NMR-and MS-based identification and dereplication strategies aided by artificial intelligence and machine learning algorithms have brought about a significant shift in the natural products discovery process. These developments and changes in the natural products filed have given us insights into how to accurately target and mining nutritional, functional, and bioactive compounds. Thus, we have summarized recent research on novel NMR and MS based strategies and methods focusing on functional compounds, accurate identification and efficient discovery mainly in medicinal and dietary plants. This review could provide a comprehensive perspective for a better understanding of novel strategies and methods based on NMR and MS technologies, which could provide valuable insights and ideas for functional compounds mining.

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Section: Ms-based Discovery Strategy For Fcs and Nps Analysismentioning

confidence: 99%

The application and perspective of NMR and MS based strategies for functional compounds mining in medicinal and dietary plants

Zhang,

Li,

Liang

et al. 2024

Food Science and Human Wellness

View full text Add to dashboard Cite

show abstract

“…The plant is rich in biologically active phytocompounds and those primarily belong to the categories of steroidal lactones and alkaloids [29] . Such phytocompounds isolated from the plant's leaves, roots and fruits have been reported to have antioxidant and antibacterial activities [75] . Studies also reveal that the plant extract has antitumor, antibacterial, aphrodisiac, antiviral, and cardiovascular protection activities [76] .…”

Section: Generalized Chemical Composition Structure Biological Activi...mentioning

confidence: 99%

Immunomodulatory Phytocompounds from Withania somnifera (L.) Dunal (Ashwagandha) Against COVID-19

Singha,

Ghosh,

Ghosh

2024

Trends Immunother.

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Withania somnifera is a famous medicinal plant. It is popularly known as Aswagandha. This plant has been in use in Ayurveda and Unani medicine for ages. The medicinal plant has immense medicinal properties. The plant is rich in potent medicinal phytocompounds. These phytocompounds are known to have potent antioxidant, antiviral, antibacterial and immunomodulatory efficacies. Our immune system is the key player in n fighting back any kind of pathogeni attack on us. Withania somnifera extract and certain isolated phytocompounds from the plant are known to boost our immune system. Studies show that the mechanisms of immunomodulatory actions of the bioactive phytocompounds from Withania somnifera are by affecting the various cellular signaling pathways. These primarily involve the signaling pathways associated with the receptors present on the vital immune cells like the dendritic cells, T-cells and B-cells. Thus, some of the compounds of Withania suppress or activate certain components of the innate and adaptive immune system. Unlike synthetic adjuvants, the natural plant derived phytocompounds and their derivatives, as those from the Withania sp. are free from such risk factors. A strong immune system is the best possession to fight back invasions by microbes like bacteria and viruses like the SARS-CoV-2. Detailed and compact knowledge of the compounds from Withania sp. and their mechanism of modulating and impacting our immune system may make the ways for development of new supportive therapies against almost all different types of diseases including COVID 19.

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Withanolides from Physalis peruviana

Coy-Barrera

2024

Handbook of Goldenberry (Physalis Peruviana)

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Exploring phytochemicals of Withania somnifera from different vicinity for functional foods

Cited by 5 publications

References 37 publications

The application and perspective of NMR and MS based strategies for functional compounds mining in medicinal and dietary plants

The application and perspective of NMR and MS based strategies for functional compounds mining in medicinal and dietary plants

Immunomodulatory Phytocompounds from Withania somnifera (L.) Dunal (Ashwagandha) Against COVID-19

Withanolides from Physalis peruviana

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