Exploring risk and protective mechanisms associated with HIV infection among adolescents in South Africa

Naidoo, Pamela; Donenberg, Geri R.; Davids, A.; Jonas, Kim; Vermaak, Redwaan; Simbayi, Leickness C.; Kagee, Ashraf; Ward, Catherine L.; Emersen, E.

doi:10.1080/14330237.2014.906080

Cited by 5 publications

(4 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Emotional connectedness has been shown to be protective against risky sexual behaviour that can lead to unplanned pregnancy, HIV and other sexually transmitted infections (Wamoyi & Wight, 2014). This reflects other findings that adolescents who experience family support, cohesion, connectedness and close relationships are likely to have fewer sexual contacts, engage in less risky sexual behaviours, show increased contraceptive usage and delay sexual debut (Naidoo, Donenberg, Davids, Jonas, Vermaak, Simbayi, Kagee, Ward & Emersen, 2014).…”

Section: Figure 2 Theory Of Changementioning

confidence: 70%

Cash Transfers and Caregivers: Working Together to Reduce Vulnerability and Hiv Risk Among Adolescent Girls in Johannesburg, South Africa

Hill

Hochfeld

Patel

2021

SWORK

View full text Add to dashboard Cite

In South Africa adolescent girls have the highest HIV incidence of any sex or age cohort. Scalable HIVprevention interventions targeting this group are critical for epidemic control. Reaching 12.2 million children, the Child Support Grant mitigates the socio-structural drivers of HIV risk. This qualitative study of eight adolescents and their caregivers in Westbury, Johannesburg, explored how caregiving increases protective potential. 'Caregiving' enhanced the HIV risk-reduction benefits of 'cash' when characterised by substantial positive caregiver-adolescent involvement and adequate levels of control and consistency. Results underpin the value of social protection as an HIV-prevention modality and endorse investment in caregiver support programmes.

show abstract

Section: Figure 2 Theory Of Changementioning

confidence: 70%

Cash Transfers and Caregivers: Working Together to Reduce Vulnerability and Hiv Risk Among Adolescent Girls in Johannesburg, South Africa

Hill

Hochfeld

Patel

2021

SWORK

View full text Add to dashboard Cite

show abstract

“…Based on validated adult HIV risk calculators,17 18 age category, financial support, alcohol use, contraceptive use, pregnancy, prior HIV testing and HSV-2 serostatus were included in our tool. We also incorporated risk variables unique to adolescents, including HIV knowledge,1 21 school absence22 and perceived HIV risk,23 to account for potential dimensions of adolescent risk not captured by adult risk tools (online supplementary dictionary).…”

Section: Methodsmentioning

confidence: 99%

“…While data on adolescents are scarce, the CAPRISA 007 (CAP007) trial provides a unique and valuable opportunity to explore HIV risk and behaviours among adolescent female students 19 20. These analyses use data from one of the highest HIV burden health districts in rural KwaZulu-Natal to assess an adapted risk tool, including characteristics from validated tools for HIV prediction in adults,17 18 as well as adolescent risk characteristics (knowledge,1 21 school attendance22 and perceived risk) 23. First, we assess latent risk factors, or dimensions of adolescent risk, underlying risk variables captured with our tool.…”

Section: Introductionmentioning

confidence: 99%

Development of a prognostic tool exploring female adolescent risk for HIV prevention and PrEP in rural South Africa, a generalised epidemic setting

et al. 2019

View full text Add to dashboard Cite

ObjectivesAdolescent females in sub-Saharan Africa bear a disproportionate burden of new HIV infections but have been excluded from prognostic research, such as developed risk calculators. This study examines whether validated risk calculators, which calculate HIV risk among sub-Saharan African women, can be modified to assess HIV risk among adolescent girls. The performance of selected risk variables from validated calculators and the literature was evaluated among adolescent females using modern advanced statistical tools.MethodsRisk variables for the updated tool were selected from the CAPRISA 007 (CAP007) trial (2010–2012) questionnaires. An initially HIV-seronegative cohort of rural South African female high school students (n=1049) aged 14–25 years was selected. The number and characteristics of latent factors, or dimensions, underlying selected variables were assessed using exploratory factor analysis (EFA). The updated tool’s effectiveness identifying trends in adolescent risk were assessed with latent class analysis (LCA).ResultsEFA identified two key latent factors: sexual behaviour and socioeconomic risk factors. Latent sexual behaviour risk influenced contraception use (0.883), perceived HIV risk (0.691) and pregnancy (−0.384). Latent socioeconomic risk influenced low HIV knowledge (0.371), financial dependence (0.532), prior HIV testing (−0.379) and alcohol use (−0.332). Using LCA, three underlying categories of adolescent females were identified: those with no, low and high risk of HIV (1.10%, 2.26% and 2.91% 1-year seroconversion rates, respectively). Herpes simplex virus serotype-2, condom contraception, alcohol use, pregnancy and age were significantly associated with higher risk class membership, while non-condom contraception was associated with lower risk class membership.ConclusionsAdolescent females are at unequal risk of acquiring HIV. Findings suggest the updated tool captures two main facets of adolescent characteristics and may identify differential risk. This work supports further investigation to inform development of targeted differentiated interventions and efficient prognostic tools for adolescents in high-risk settings.

show abstract

“…[44,45] In our study, the overwhelming majority of adolescents expressed relief and gratitude in being able to tell their story and did not report experiencing the interview as stressfulechoing findings in other studies of HIV-affected children. [46][47][48] The African Charter on the Rights and Responsibilities of the Child recognises rights to enjoy the best attainable state of physical, mental and spiritual health and scientific research. The right to life and the right to access to healthcare rank among the most fundamental of the human rights guaranteed by international human rights.…”

Section: Inadvertent Harm or Silence To Voices That Most Need To Be Hmentioning

confidence: 99%

Enrolling HIV-positive adolescents in mental health research: A case study reflecting on legal and ethical complexities

Woollett

Peter²,

Cluver

et al. 2017

S Afr Med J

View full text Add to dashboard Cite

Exploring risk and protective mechanisms associated with HIV infection among adolescents in South Africa

Cited by 5 publications

References 33 publications

Cash Transfers and Caregivers: Working Together to Reduce Vulnerability and Hiv Risk Among Adolescent Girls in Johannesburg, South Africa

Cash Transfers and Caregivers: Working Together to Reduce Vulnerability and Hiv Risk Among Adolescent Girls in Johannesburg, South Africa

Development of a prognostic tool exploring female adolescent risk for HIV prevention and PrEP in rural South Africa, a generalised epidemic setting

Enrolling HIV-positive adolescents in mental health research: A case study reflecting on legal and ethical complexities

Contact Info

Product

Resources

About