Exploring the association of PM2.5 with lung cancer incidence under different climate zones and socioeconomic conditions from 2006 to 2016 in China

Guo, Bin; Gao, Qian; Pei, Lin; Guo, Tengyue; Wang, Yan; Wu, Haojie; Zhang, Wencai; Chen, Miaoyi

doi:10.1007/s11356-023-31138-8

Cited by 3 publications

(2 citation statements)

References 68 publications

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“…Based on the top 15 keywords with the strongest citation bursts, a clear topic trend in the fields of environmental pollution and lung cancer was shown ( Figure 2 B). The hot topic in this area has gradually shifted from chemical pollution (e.g., polycyclic aromatic hydrocarbons) to air pollution, with PM2.5 and particulate matter being hotspots in air pollution and lung cancer [ 27 ]. However, the effect of biological pollution on lung cancer has not been emphasized in the last 20 years of environmental pollution research based on the results of the bibliometric analysis.…”

Section: Air Pollution and Lung Cancermentioning

confidence: 99%

Dark under the Lamp: Neglected Biological Pollutants in the Environment Are Closely Linked to Lung Cancer

Wang,

Chan,

Zhang

et al. 2024

IJMS

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Environmental pollutants are closely linked to lung cancer. The different types of environmental pollutants can be classified as chemical, physical, and biological. The roles of common chemical and physical pollutants such as PM2.5, smoking, radon, asbestos, and formaldehyde in lung cancer have been extensively studied. Notably, the worldwide COVID-19 pandemic raised awareness of the strong link between biological pollution and human health. Allergens such as house dust mites and pollen, as well as bacteria and viruses, are common biological pollutants. A few biological pollutants have been reported to promote lung cancer via inducing inflammatory cytokines secretion, such as IL-1β, IL-6, and TGF-β, as well as suppressing immunosurveillance by upregulating regulatory T (Treg) cells while dampening the function of CD8+ T cells and dendritic cells. However, the correlation between common biological hazards, such as SARS-CoV-2, human immunodeficiency viruses, Helicobacter pylori, and house dust mites, and lung cancer is not fully elucidated, and the underlying mechanisms are still unclear. Moreover, the majority of studies that have been performed in lung cancer and biological carcinogens were not based on the perspective of biological pollutants, which has challenged the systematicity and coherence in the field of biological pollutants in lung cancer. Here, in addition to reviewing the recent progress made in investigating the roles of allergens, viruses, and bacteria in lung cancer, we summarized the potential mechanisms underlying biological pollutants in lung cancer. Our narrative review can shed light on understanding the significance of biological pollutants in lung cancer, as well as inspire and broaden research ideas on lung cancer etiology.

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Section: Air Pollution and Lung Cancermentioning

confidence: 99%

Dark under the Lamp: Neglected Biological Pollutants in the Environment Are Closely Linked to Lung Cancer

Wang,

Chan,

Zhang

et al. 2024

IJMS

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“…Indeed, outdoor air pollutants, including particulate matter 2.5 μm or less in diameter (PM 2.5 ), have been defined as carcinogenic to humans by the International Agency for Research on Cancer [ 19 ]. Guo et al found a positive association between PM 2.5 air concentration and lung cancer incidence in China, showing a major impact of PM 2.5 on health in regions with extreme climate conditions [ 20 ].…”

Section: Climate Change In Health and Diseasementioning

confidence: 99%

The Impact of Climate Change on Immunity and Gut Microbiota in the Development of Disease

Rio,

Caldarelli,

Gasbarrini

et al. 2024

Diseases

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According to the definition provided by the United Nations, “climate change” describes the persistent alterations in temperatures and weather trends. These alterations may arise naturally, such as fluctuations in the solar cycle. Nonetheless, since the 19th century, human activities have emerged as the primary agent for climate change, primarily attributed to the combustion of fossil fuels such as coal, oil, and gas. Climate change can potentially influence the well-being, agricultural production, housing, safety, and employment opportunities for all individuals. The immune system is an important interface through which global climate change affects human health. Extreme heat, weather events and environmental pollutants could impair both innate and adaptive immune responses, promoting inflammation and genomic instability, and increasing the risk of autoimmune and chronic inflammatory diseases. Moreover, climate change has an impact on both soil and gut microbiome composition, which can further explain changes in human health outcomes. This narrative review aims to explore the influence of climate change on human health and disease, focusing specifically on its effects on the immune system and gut microbiota. Understanding how these factors contribute to the development of physical and mental illness may allow for the design of strategies aimed at reducing the negative impact of climate and pollution on human health.

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A systematic review of spatial and temporal epidemiological approaches, focus on lung cancer risk associated with particulate matter

Neupane,

Acharya,

Cao

et al. 2024

BMC Public Health

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Background Particulate matter (PM), including the major risk factor for lung cancer (LC), greatly impacts human health. Although numerous studies have highlighted spatiotemporal patterns and PM-LC associations, these studies have not been well-reviewed. Thus, we examined epidemiological studies linked with PM-LC and provided concise, up-to-date data. Methods We used certain keywords to review articles published in PubMed, Web of Science, Scopus, and Google Scholar until 30th June 2024 and identified 1474 research articles. We then filtered the research articles based on our criteria and ultimately dropped down to 30 for this review. Results Out of the thirty reviewed studies on the PM-LC relation, twenty-four focused on PM 2.5 , four on PM 10 , and two on both, indicating that approximately 80% of the respondents were inclined toward fine particles and their health impacts. The study revealed that 22 studies used visualization, 12 used exploration, and 15 used modeling methods. A strong positive relationship was reported between LC and PM 2.5 , ranging from 1.04 to 1.60 (95% CI) for a 10 µg/m 3 increase in PM 2.5 exposure. However, compared to PM 2.5 , PM 10 was found to have a significantly less positive association. Conclusions Very few studies have used advanced spatiotemporal methods to examine the association between LC and PM. Advanced spatiotemporal analysis techniques should be employed to explore this association in specific geographical locations. Further research should utilize spatiotemporal epidemiological approaches to study the link between PM and lung cancer.

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Exploring the association of PM2.5 with lung cancer incidence under different climate zones and socioeconomic conditions from 2006 to 2016 in China

Cited by 3 publications

References 68 publications

Dark under the Lamp: Neglected Biological Pollutants in the Environment Are Closely Linked to Lung Cancer

Dark under the Lamp: Neglected Biological Pollutants in the Environment Are Closely Linked to Lung Cancer

The Impact of Climate Change on Immunity and Gut Microbiota in the Development of Disease

A systematic review of spatial and temporal epidemiological approaches, focus on lung cancer risk associated with particulate matter

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