Exploring the Contribution of Autophagy to the Excess-Sucrose Response in Arabidopsis thaliana

Laloum, Daniel; Magen, Sahar; Soroka, Yoram; Avin‐Wittenberg, Tamar

doi:10.3390/ijms23073891

Cited by 3 publications

(2 citation statements)

References 113 publications

(169 reference statements)

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“…In addition, the root meristem of the wild-type plants appeared to be shorter under high glucose and sucrose concentrations. The authors postulated the differential response stems from altered ROS detoxification and auxin accumulation in atg mutant and wild-type roots [79,80]. These data suggest that autophagy might play a role in maintaining plant carbon balance.…”

Section: Autophagy and Carbon Availabilitymentioning

confidence: 99%

Metabolism and autophagy in plants—a perfect match

et al. 2022

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Autophagy is a eukaryotic cellular transport mechanism that delivers intracellular macromolecules, proteins, and even organelles to a lytic organelle (vacuole in yeast and plants/lysosome in animals) for degradation and nutrient recycling. The process is mediated by highly conserved autophagy-related (ATG) proteins. In plants, autophagy maintains cellular homeostasis under favorable conditions, guaranteeing normal plant growth and fitness. Severe stress such as nutrient starvation and plant senescence further induce it, thus ensuring plant survival under unfavorable conditions by providing nutrients through the removal of damaged or aged proteins, or organelles. In this article, we examine the interplay between metabolism and autophagy, focusing on the different aspects of this reciprocal relationship. We show that autophagy has a strong influence on a range of metabolic processes, whereas at the same time, even single metabolites can activate autophagy. We highlight the involvement of ATG genes in metabolism, examine the role of the macronutrients carbon and nitrogen, and various micronutrients, and take a closer look at how the interaction between autophagy and metabolism impacts on plant phenotypes and yield.

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Section: Autophagy and Carbon Availabilitymentioning

confidence: 99%

Metabolism and autophagy in plants—a perfect match

et al. 2022

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“…Expansin proteins are essential to the processes of cell elongation and division, as well as multiple abiotic stress responses [8]. Expansins are common in plants and are categorized into four subfamilies: expansin-like B (EXLB), expansin-like A (EXLA), β-expansin (EXPB), and α-expansin (EXPA) [9].…”

Section: Introductionmentioning

confidence: 99%

The SbbHLH041–SbEXPA11 Module Enhances Cadmium Accumulation and Rescues Biomass by Increasing Photosynthetic Efficiency in Sorghum

Wang,

Yu,

Zhu

et al. 2023

IJMS

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In plants, expansin genes are responsive to heavy metal exposure. To study the bioremediary potential of this important gene family, we discovered a root-expressed expansin gene in sorghum, SbEXPA11, which is notably upregulated following cadmium (Cd) exposure. However, the mechanism underlying the Cd detoxification and accumulation mediated by SbEXPA11 in sorghum remains unclear. We overexpressed SbEXPA11 in sorghum and compared wild-type (WT) and SbEXPA11-overexpressing transgenic sorghum in terms of Cd accumulation and physiological indices following Cd. Compared with the WT, we found that SbEXPA11 mediates Cd tolerance by exerting reactive oxygen species (ROS)-scavenging effects through upregulating the expression of antioxidant enzymes. Moreover, the overexpression of SbEXPA11 rescued biomass production by increasing the photosynthetic efficiency of transgenic plants. In the pot experiment with a dosage of 10 mg/kg Cd, transgenic sorghum plants demonstrated higher efficacy in reducing the Cd content of the soil (8.62 mg/kg) compared to WT sorghum plants (9.51 mg/kg). Subsequent analysis revealed that the SbbHLH041 transcription factor has the ability to induce SbEXPA11 expression through interacting with the E-box located within the SbEXPA11 promoter. These findings suggest that the SbbHLH041–SbEXPA11 cascade module may be beneficial for the development of phytoremediary sorghum varieties.

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The lowdown on breakdown: Open questions in plant proteolysis

Eckardt,

Avin-Wittenberg,

Bassham

et al. 2024

The Plant Cell

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Proteolysis, including post-translational proteolytic processing as well as protein degradation and amino acid recycling, is an essential component of the growth and development of living organisms. In this article, experts in plant proteolysis pose and discuss compelling open questions in their areas of research. Topics covered include the role of proteolysis in the cell cycle, DNA damage response, mitochondrial function, the generation of N-terminal signals (degrons) that mark many proteins for degradation (N-terminal acetylation, the Arg/N-degron pathway, and the chloroplast N-degron pathway), developmental and metabolic signaling (photomorphogenesis, abscisic acid and strigolactone signaling, sugar metabolism, and post-harvest regulation), plant responses to environmental signals (endoplasmic-reticulum associated degradation, chloroplast-associated degradation, drought tolerance, the growth-defense tradeoff)), and the functional diversification of peptidases. We hope these thought-provoking discussions help to stimulate further research.

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Exploring the Contribution of Autophagy to the Excess-Sucrose Response in Arabidopsis thaliana

Cited by 3 publications

References 113 publications

Metabolism and autophagy in plants—a perfect match

Metabolism and autophagy in plants—a perfect match

The SbbHLH041–SbEXPA11 Module Enhances Cadmium Accumulation and Rescues Biomass by Increasing Photosynthetic Efficiency in Sorghum

The lowdown on breakdown: Open questions in plant proteolysis

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