Exploring the efficacy of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a natural compound in strengthening maize resistance against biotic and abiotic stressors: an empirical computational study

Abstract

ObjectiveThis study aims to understand plant-bacteria interactions that enhance plant resistance to environmental stressors, with a focus on maize (Zea mays L.) and its vulnerability to various pathogenic organisms. We examine the potential of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a compound to boost maize’s resilience against stressors and pathogens.BackgroundWith the growing global population and increased food demand, the study of endophytes, comprising bacteria and fungi, becomes crucial. They reside within plant tissues, affecting their hosts either beneficially or detrimentally. Agrobacteria are of specific interest due to their potential to contribute to developing strategies for plant resistance enhancement.MethodsWe conducted exhaustive research on the defense-related proteins and mechanisms involved in maize-pathogen interactions. The efficacy of ACCA as a natural-compound that could enhance maize’s resistance was examined.ResultsOur research indicates that ACCA, having a binding energy of −9.98 kcal/mol, successfully strengthens maize resistance against pathogenic assaults and drought stress. It plays a crucial protective role in maize plants as they mature, outperforming other ligands in its effectiveness to improve productivity and increase yield.ConclusionApplying ACCA to maize plants has considerable potential in enhancing their resilience and tolerance to stress, proving to be an effective strategy to boost crop yield and productivity. This could help address the increasing global food demand. However, more research is needed to optimize ACCA application methods and to gain a comprehensive understanding of its long-term effects on maize cultivations and the environment.

Enhancing drought tolerance in cauliflower (Brassica oleracea var. botrytis) by targeting LFY transcription factor modulation via the ethylene precursor, ACCA: an innovative computational approach

“…The OPLS 2005-derived force field was employed during the simulation ( Xu et al., 2023 ). The physiological circumstances present during the experiment were simulated by introducing a concentration of 0.15 M by the utilization of NaCl ( Debnath et al., 2023a ). The simulation was conducted at a temperature of 300 K and a pressure equivalent to atmospheric pressure.…”

“…Importantly, in our recent study on maize ( Zea mays L.), we explored the role of 1-amino-cyclopropane-1-carboxylic acid (ACCA) in enhancing plant resistance. We found that ACCA, with a binding energy of −9.98 kcal/mol, effectively strengthens maize against pathogens and drought stress ( Debnath et al., 2023a ). This finding is pivotal for our current research on cauliflower, as it suggests ACCA’s broader applicability in different plant species.…”