Exploring the efficacy of photodynamic antimicrobial chemotherapy on diabetic foot ulcers in rats
Zhanjuan Zhao,
Jinwen Pang,
Di Zhao
et al.
Abstract:We investigate the efficacy of photodynamic antimicrobial chemotherapy (PACT) and its combination with an antibiotic in the treatment of diabetic foot ulcers (DFUs) in rats using a novel cationic amino acid porphyrin‐based photosensitizer. The research findings demonstrate that the combination of novel cationic photosensitizer‐mediated PACT and an antibiotic exhibits significant therapeutic efficacy in treating deep ulcers in a rat model of DFUs. Moreover, the PACT + Antibiotic group displays enhanced angiogen… Show more
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