In this study, uopyram (FOR), acetamiprid (ATP) and chlorantraniliprole (CAP) were used individually or in combination at the maximum recommended dose in greenhouse strawberries to research the dissipation dynamics and dietary risks. A multi-residue analytical method for FOR, ATP and CAP in strawberries using UPLC-MS/MS integrated with QuEChERS approach was develop with a strong linearity (R 2 ≧ 0.9990), accuracy (recoveries of 82.62-107.79%), and precision (relative standard deviations of 0.58-12.73%). The limits of quanti cation were 0.01 mg kg − 1 . Field results showed that the half-lives of FOR, ATP and CAP in strawberry fruits were 11.6-12.4 days, 6.1-6.7 days and 10.9-11.7 days, respectively. The half-lives of the three investigated pesticides showed no signi cant difference when used individually or in combination. A risk assessment indicated that the dietary intake risks of the three pesticides in grown strawberries were 0.0041-7.63% whether applied alone or joint, which demonstrated that the dietary intake risks of three pesticides in grown strawberries could be negligible for Chinese male and female consumers, and even though pesticides were used in combination, there was no need to be concerned about the safety. This paper serves as a guide for the safe use of FOR, ATP and CAP on greenhouse strawberries.