Many countries of the world are transferring large budgets to health sector expenditures, the importance of which is understood more after the COVID-19 epidemic. Considering both the new branches triggered by the development of technology, the supply of personnel, and health materials needed by the sector, the amount of financial resources transferred indicates how important a financial role the individuals working in the health sector play. The starting point of this research is that health managers can make financial plans, manage the right resources correctly, how much their managerial skills and financial skills overlap, and whether these two concepts (management skills and general financial literacy) affect each other. Because the employment provided in the health sector and the fact that the actors managing the financial resources spent have sufficient financial knowledge and skills will contribute significantly to both the sustainability of the sector and the stability of the health sector. In this context, in the study, general financial literacy levels of managers working in the health sector, lower, middle and upper management levels in Adıyaman province and its districts were determined. The relationship between the determined general financial literacy level and management skills, and the effect of financial literacy on management skills have been revealed. In addition, it was also discussed whether the general financial literacy and management skills levels of managers differ in terms of their personal, generational, educational and managerial characteristics. In addition, another distinguishing feature of this work is that it is three-dimensional: First; measuring general financial literacy and management skills, second; measuring the effect of general financial literacy level on management skills and the third dimension is making these measurements in an area where very valuable resources are transferred, such as the health sector.