Exploring the heterogeneity among partially vaccinated children in a population-based cohort

Bell, Christopher; Simmonds, Kimberley; MacDonald, Shannon E.

doi:10.1016/j.vaccine.2015.07.004

Cited by 25 publications

(67 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A higher proportion of children were completely vaccinated for all recommended vaccines at age 2 in our community-based pregnancy cohort in Calgary (77%) compared to an estimate of 71% from a large, population-based Alberta birth cohort. 25 While a majority of children were vaccinated completely in our study, it was far short of the target of 97%-98% of children at age two being completely vaccinated that was set for Alberta. 3 While in our study, DTaP-IPVHib had the lowest proportion of children completing the series (85%), in the provincial birth cohort, PCV7 was the lowest at 75%.…”

Section: Discussionmentioning

confidence: 77%

“…3 While in our study, DTaP-IPVHib had the lowest proportion of children completing the series (85%), in the provincial birth cohort, PCV7 was the lowest at 75%. 25 Both these vaccines required 4 doses, with the final dose at 18 months, the time point at which the lowest proportion of timely vaccinations is seen. In the Canadian context, many mothers return from subsidized maternity leave at 12 months, which may impede the timely completion of an 18-month, 4-dose series; however, the decrease in series completion between 12 and 18 months has been recognized in the US, where mothers often return to work sooner.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Timeliness and completeness of routine childhood vaccinations in children by two years of age in Alberta, Canada

Saini

MacDonald

McNeil

et al. 2017

Can J Public Health

Self Cite

View full text Add to dashboard Cite

OBJECTIVES: Assessing timeliness and completeness of vaccine administration is important for evaluating the effectiveness of immunization programs. Few studies have reported timeliness, particularly in Canada. The objective of this study was to examine timeliness of the receipt of vaccination for each routine childhood recommended vaccine by 24 months of age among children in a community-based pregnancy cohort in Calgary, Alberta.METHODS: Survey data from a community-based pregnancy cohort in Alberta were linked to Public Health vaccination records of children (n = 2763). The proportion of children receiving early, timely, delayed, or no vaccination was calculated. A dose was considered early if it was administered before the recommended age in days as per the vaccination schedule, timely if administered at any time from start of recommended age in days to age in days when delay counts were initiated, and delayed if it was administered on or after age in days when delay counts were initiated. Series completion rates were also calculated. RESULTS:For multi-dose vaccines, over 80% of children had timely doses at 2, 4 and 6 months. By 12 months, this proportion decreased to 65% (95% CI: 63%-66%) for meningococcal conjugate group C, 61% (95% CI: 59%-62%) for measles antigen-containing vaccines and 64% (95% CI: 62%-65%) for varicella antigen-containing vaccines. At 18 months, only 55% (95% CI: 53%-56%) of the children had a timely 4 th dose of diphtheria, acellular pertussis, tetanus, polio, and Haemophilus influenzae type b vaccine. Eventual series completion rate for all recommended vaccines was 77% (95% CI: 75%-79%). CONCLUSION:The timeliness and completeness of routine childhood vaccination in preschool children in this community-based pregnancy cohort is lower than provincial targets. Data on timeliness of vaccination can inform further work on barriers and enablers to vaccination in order to meet provincial targets.KEY WORDS: Vaccination; immunization; timeliness; completeness; child La traduction du résumé se trouve à la fin de l'article.

show abstract

Section: Discussionmentioning

confidence: 77%

Section: Discussionmentioning

confidence: 99%

Timeliness and completeness of routine childhood vaccinations in children by two years of age in Alberta, Canada

Saini

MacDonald

McNeil

et al. 2017

Can J Public Health

Self Cite

View full text Add to dashboard Cite

show abstract

“…Further, shot-limited children having a midwife birth attendant were less likely to be up-to-date than shot-limited children having a medical doctor birth attendant. A study by Bell et al similarly determined that parents who delayed vaccinations were more likely to use midwife birth attendants [17]. Our analysis does not address why shot-limited children who had midwife attendants were less likely to be up-to-date.…”

Section: Discussionmentioning

confidence: 85%

“…Recent studies have indicated that the number of undervaccinated children is greater than nonvaccinated and this population is growing [13,17]. To reach the Healthy People 2020 goal of achieving 80% coverage for the combined series of seven ACIP-recommended vaccines among children ages 19–35 months, we must understand the factors associated with undervaccination and target increased public health interventions aimed at increasing timely receipt of vaccination.…”

Section: Discussionmentioning

confidence: 99%

Vaccine shot-limiting: Estimating the prevalence, indicators, and impact on vaccination status — Michigan, 2012

Weinberg

Dietz

Potter

et al. 2017

Vaccine

View full text Add to dashboard Cite

Background Concerns regarding vaccine safety and pain have prompted certain parents to limit the number of shots their child receives per visit. We estimated the prevalence of shot-limited children in Michigan, described their characteristics, assessed whether shot-limited children were up-to-date on recommended vaccinations, and investigated possible intervention points for vaccination education. Methods We analyzed vaccination registry and birth record data of children born in Michigan during 2012 who had ⩾2 vaccination visits, with ⩾1 visits after age 5 months. Shot-limited was defined as receiving ≤2 shots at all visits through age 24 months. Nonlimited children received >2 shots at ⩾1 visits. Up-to-date vaccination was based on receipt of a seven-vaccine series and was determined at ages 24 months and 35 months. Risk ratios (RR) were calculated using risk regression. Results Of 101,443 children, a total of 2,967 (3%) children were shot-limited. Mothers of shot-limited children were more likely to be white (RR: 1.2; 95% confidence interval [CI]: 1.2–1.2), college graduate (RR: 1.9; 95% CI: 1.9–2.0), and married (RR: 1.5; 95% CI: 1.5–1.5). Compared with nonlimited children, shot-limited children were more likely to be born in a nonhospital setting (RR: 11.7; 95% CI: 9.4–14.6) and have a midwife attendant (RR: 1.9; 95% CI: 1.7–2.1). Shot-limited children were less likely to be up-to-date on recommended vaccinations (RR: 0.2; 95% CI: 0.2–0.3); this association was stronger for those with a midwife birth attendant (RR: 0.1; 95% CI: 0.1–0.2) rather than a medical doctor (RR: 0.3; 95% CI: 0.2–0.3). Conclusions Shot-limited children are less likely to be up-to-date on vaccinations, possibly leading to increased risk for vaccine-preventable diseases. This association was stronger for those with a midwife birth attendant. This analysis should prompt targeted education, such as to midwives, concerning risks associated with shot-limiting behavior.

show abstract

“…16,17 This may be due to women who choose midwifery care having alternative beliefs regarding health care interventions, as evidenced by recent literature showing decreased vaccination rates and neonatal vitamin K prophylaxis among children born to women who sought midwife care. 18,19 This trend might also be due to midwifery's principles of encouraging informed choice for independent decision making. 20,21 Women using midwives in our cohort were older, and less likely to be First Nations, single and in the lowest income quintile than women not using midwives.…”

Section: Discussionmentioning

confidence: 99%

Examination of a prenatal syphilis screening program, Alberta, Canada: 2010–2011

Plitt

Osman

Sahni

et al. 2016

Can J Public Health

View full text Add to dashboard Cite

OBJECTIVES: In 2009, due to increasing congenital syphilis rates, prenatal syphilis tests (PST) at both mid-gestation and delivery were added to first trimester prenatal screening in the province of Alberta. We sought to determine the proportion of mothers who had all three recommended PSTs during this period and to identify factors associated with incomplete PST. METHODS:A cohort of all pregnancies resulting in a live or stillborn infant in Alberta for 2010 and 2011 was developed from Vital Statistics and linked with prenatal screening data to determine the number and timing of PSTs for pregnant women. The proportion of women who had PSTs at the three recommended time points in pregnancy and associated correlates were identified using basic statistics and logistic regressions. RESULTS:Of 99,609 pregnancies, 20.7% had all three PSTs at the recommended time points. Overall, 98.5% (98,162) had at least one PST, 1.5% only had PST at delivery and 1.5% had no PST performed. Independent risk factors for not having the three recommended PSTs CONCLUSIONS: Nearly all pregnant women in Alberta received a PST at least once during their pregnancy, however far fewer received PSTs at the recommended time points. Interventions that target those who are less likely to be prenatally screened may help to ensure that pregnant women get early and appropriate care for syphilis during pregnancy.KEY WORDS: Prenatal diagnosis; syphilis; prenatal care; Canada La traduction du résumé se trouve à la fin de l'article.

show abstract

Exploring the heterogeneity among partially vaccinated children in a population-based cohort

Cited by 25 publications

References 27 publications

Timeliness and completeness of routine childhood vaccinations in children by two years of age in Alberta, Canada

Timeliness and completeness of routine childhood vaccinations in children by two years of age in Alberta, Canada

Vaccine shot-limiting: Estimating the prevalence, indicators, and impact on vaccination status — Michigan, 2012

Examination of a prenatal syphilis screening program, Alberta, Canada: 2010–2011

Contact Info

Product

Resources

About