Exploring the Impact of Allogeneic Gamma Delta T Cell Adoptive Transfer on HIV Replication in a Humanized Mouse Model

Abstract

Human immunodeficiency virus (HIV) remains a persistent global health challenge, necessitating ongoing exploration of innovative therapeutic strategies. This study investigates the consequences of adoptive transfer of allogeneic gamma delta (γδ) T cells on HIV replication using a humanized mouse model. The research aims to uncover the potential risks and benefits associated with this therapeutic approach, with a specific focus on its effects on viral load, immune response, and overall host health.