Exploring the impact of diabetes on the prognosis of gastric cancer patients based on the survival data of gastric cancer patients in NHANES database and the survival data of Chinese gastric cancer patients

Abstract

Objectives At present, the prognosis of gastric cancer patients is poor, and many factors affect their prognosis. This study mainly explored the relationship between diabetes and the prognosis of patients with gastric cancer. Methods Collect clinical data of gastric cancer patients from the NHANES database from 1999 to 2020 and the First Affiliated Hospital of Anhui Medical University from 2015 to 2017. Integrating survival time, survival status, and covariates affecting prognosis in gastric cancer patients. To explore the relationship between diabetes and prognosis of gastric cancer patients by univariate and multivariate cox regression analysis Results In the clinical data of gastric cancer patients in NHANES database, in the three models constructed, there were differences between the history of diabetes and the prognosis of gastric cancer patients (p < 0.05). In the clinical data of gastric cancer patients in the first affiliated hospital of anhui medical university, there were differences between diabetes and gastric cancer prognosis in univariate and multivariate cox regression analysis (p < 0.05). Conclusions By analyzing the clinical data of gastric cancer patients in NHANES database and the First Affiliated Hospital of Anhui Medical University, we found that diabetes is a risk prognostic factor for gastric cancer.