Increasingly, research, teaching, and practice emphasize the need for cultural competency among healthcare practitioners. Most training programmes include modules on cultural competency based on a knowledge, skills, and awareness model. In line with the knowledge and awareness objectives of cultural competency, this article focuses on the conceptualization of illness from an Islamic, Hindu, and African perspective. It discusses spiritual illness, a category of illness recognized in all three traditions but marginalized in mainstream literature. This marginalization has given rise to debates as to whether a separate Islamic psychology, a Hindu psychology, African psychology (or other Psychology) should exist. This article explores these areas briefly concluding with arguments on the need for current teaching, research, and practice to take more cognizance of cultural views of illness.