Exploring the interactions between polyunsaturated fatty acids and cadmium in rainbow trout liver cells: a genetic and proteomic study

Evidence of Contamination-Associated Damage in Blue Sharks (Prionace Glauca) from the Northeast Atlantic

“…While the negative correlation between contaminants and ROS in the liver is somehow unexpected but could be potentially related to the over induction of the antioxidant system, an apparent decrease in LPO in that tissue may occur with the increase of contaminants if the exposure leads to a reduction in levels of highly unsaturated fatty acids, which are very susceptible to being oxidized (Hsieh and Kinsella, 1989). Since studies have shown that exposure to different stressors, including contaminants, can induce alterations in the fatty acid profile (FAP) of fish (Ferain et al, 2018;Gonçalves et al, 2021;Liao et al, 2019), and differences in FAP have been reported in elasmobranchs exhibiting different contamination profiles (Rosenfelder et al, 2012), it would be valuable to perform an evaluation of the fatty acid profile of these sharks' liver and assess if these more contaminated individuals would indeed show a reduction in highly unsaturated fatty acids. In the gills, the observed negative correlation between contaminants and damaged DNA may be associated with the histological lesions observed.…”

Protein Signatures to Trace Seafood Contamination and Processing

“…Similarly, the amount and composition of the feed taken by the fish prior to its death [60] (which affects its shelf life [81,82] and taste [83], respectively) and freshness and processing methods [51] have been examined by proteomics techniques. From the point of view of seafood safety, proteomics has been applied to identifying markers of exposure to traditional hazards, such as biotoxins [61,62] and environmental pollutants [63][64][65][66][67].…”

Antagonistic bioaccumulation of waterborne Cu(II) and Cd(II) in common carp (Cyprinus carpio) and effects on ion-homeostasis and defensive mechanisms

“…Non-essential metal species such as those of mercury (Hg), lead (Pb) and cadmium (Cd) have no known biological function in vertebrates and are toxic even at low concentrations (Danabas et al 2018). Cd 2+ is considered a threat for animals because it can alter ionoregulation, modulate protein structure and generate oxidative stress (Ferain et al 2018). Toxic effects induced by Cd can result in hypocalcaemia, as a result of the competition between calcium (Ca 2+ ) and Cd 2+ (Cinier et al 1997, McGeer et al 2011.…”