2024
DOI: 10.1088/1361-6528/ad4556
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Exploring the interplay between the TGF-β pathway and SLN-mediated transfection: implications for gene delivery efficiency in prostate cancer and non-cancer cells

Thaís Moraes-Lacerda,
Fernanda Garcia-Fossa,
Marcelo Bispo de Jesus

Abstract: Solid lipid nanoparticles (SLN) are widely recognized for their biocompatibility, scalability, and long-term stability, making them versatile formulations for drug and gene delivery. Cellular interactions, governed by complex endocytic and signaling pathways, are pivotal for the successful application of SLN as therapeutic agents. This study aims to enhance our understanding of the intricate interplay between SLN and cells by investigating the influence of specific endocytic and cell signaling pathways, with a… Show more

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