Phys. Chem. Chem. Phys.
 2024
DOI: 10.1039/d4cp00844h
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Exploring the mechanism of action of spirooxindoles as a class of CDK2 inhibitors: a structure-based computational approach

Muhammad Ikhlas Abdjan,
Muhammad Shafiq,
Dmitry Nerukh
et al.

Abstract: Cyclin-dependent kinase 2 (CDK2) regulates cell cycle checkpoints in the synthesis and mitosis phases and plays a pivotal role in cancerous cell proliferation. The activation of the CDK2, influenced by...

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