2023
DOI: 10.1016/j.ejso.2023.106999
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Exploring the potential appropriateness of high ligation for a specific demographic

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“…The study found no significant differences in the distant recurrence rate (15.8% vs. 18.9%; p = 0.970), pelvic recurrence rate (4.9% vs. 3.2%; p = 0.843), 5-year OS (80.8% vs. 81.9%; p = 0.545), and DFS (79.2% vs. 78%; p = 0.985) between the HTL and LTL, respectively [ 84 ]. Despite its randomized controlled design, the study exhibits several limitations, particularly in terms of the potential influence of preoperative treatments and the precise documentation of the locations of local or distant recurrence within both the HTL and LTL groups [ 85 ]. Additionally, since the sample size calculation was primarily tailored for evaluating GU rather than oncological outcomes, the study may be underpowered.…”
Section: The Surgeon- and Patient-centric Approach: The Different Lev...mentioning
confidence: 99%
“…The study found no significant differences in the distant recurrence rate (15.8% vs. 18.9%; p = 0.970), pelvic recurrence rate (4.9% vs. 3.2%; p = 0.843), 5-year OS (80.8% vs. 81.9%; p = 0.545), and DFS (79.2% vs. 78%; p = 0.985) between the HTL and LTL, respectively [ 84 ]. Despite its randomized controlled design, the study exhibits several limitations, particularly in terms of the potential influence of preoperative treatments and the precise documentation of the locations of local or distant recurrence within both the HTL and LTL groups [ 85 ]. Additionally, since the sample size calculation was primarily tailored for evaluating GU rather than oncological outcomes, the study may be underpowered.…”
Section: The Surgeon- and Patient-centric Approach: The Different Lev...mentioning
confidence: 99%