Exploring the potential of microwaves and ultrasounds in the green extraction of bioactive compounds from Humulus lupulus for the food and pharmaceutical industry

Carbone, Katya; Macchioni, Valentina; Petrella, Greta; Cicero, Daniel O.

doi:10.1016/j.indcrop.2020.112888

Cited by 53 publications

(57 citation statements)

References 59 publications

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“…Accurate characterization of major and minor metabolites of beer consistent with previous studies is also provided in this paper (see Section 2.2.3). Evidence for the presence of trigonelline [19] confirms rather recent experimental findings which relate its origin to the addition of hops [42,43].…”

Section: Introductionsupporting

confidence: 86%

A Metabolomic Approach to Beer Characterization

et al. 2021

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The consumers’ interest towards beer consumption has been on the rise during the past decade: new approaches and ingredients get tested, expanding the traditional recipe for brewing beer. As a consequence, the field of “beeromics” has also been constantly growing, as well as the demand for quick and exhaustive analytical methods. In this study, we propose a combination of nuclear magnetic resonance (NMR) spectroscopy and chemometrics to characterize beer. 1H-NMR spectra were collected and then analyzed using chemometric tools. An interval-based approach was applied to extract chemical features from the spectra to build a dataset of resolved relative concentrations. One aim of this work was to compare the results obtained using the full spectrum and the resolved approach: with a reasonable amount of time needed to obtain the resolved dataset, we show that the resolved information is comparable with the full spectrum information, but interpretability is greatly improved.

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Section: Introductionsupporting

confidence: 86%

A Metabolomic Approach to Beer Characterization

et al. 2021

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“…The choice of the appropriate solvent from the point of view of the utilization of the extraction, but also its impact on the environment, is one of the most important factors in the selection of an extraction technique. Although some authors have highlighted methanol as the best solvent for the extraction of bioactive plant constituents [ 63 , 64 ], the use of so-called GRAS (generally recognized as safe) solvents such as water or aqueous ethanol solutions is a desirable alternative for the further use of the extracts obtained in the cosmetic, food and pharmaceutical industries [ 65 , 66 ]. Consequently, from the results presented in Figure 2 , we can generally conclude that 80% EtOH represents a good extraction solvent for isolation of bioactive components from plant material of Zingiberaceae species.…”

Section: Resultsmentioning

confidence: 99%

Comparative Study of Chemical Composition and Antioxidant Activity of Essential Oils and Crude Extracts of Four Characteristic Zingiberaceae Herbs

Ivanović

Makoter

Razboršek

2021

Plants

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The ginger family (Zingiberaceae) includes plants that are known worldwide to have a distinctive smell and taste, which are often used as spices in the kitchen, but also in various industries (pharmaceutical, medical, and cosmetic) due to their proven biological activity. The aim of this study was to investigate and compare the chemical composition and antioxidant activity (AA) of essential oils (EOs) of four characteristic ginger species: Elettaria cardamomum L. Maton (cardamom), Curcuma Longa L. (turmeric), Zingiber Officinale Roscoe (ginger), and Alpinia Officinarum Hance (galangal). Furthermore, the total phenolic content (TPC) and AA of crude extracts obtained after using ultrasound-assisted extraction (UAE) and different extraction solvents (80% ethanol, 80% methanol and water) were evaluated. A total of 87 different chemical components were determined by GC-MS/MS in the EOs obtained after hydrodistillation, 14 of which were identified in varying amounts in all EOs. The major compounds found in cardamom, turmeric, ginger, and galangal were α-terpinyl acetate (40.70%), β-turmerone (25.77%), α-zingiberene (22.69%) and 1,8-cineol (42.71%), respectively. In general, 80% ethanol was found to be the most effective extracting solvent for the bioactivities of the investigated species from the Zingiberaceae family. Among the crude extracts, ethanolic extract of galangal showed the highest TPC value (63.01 ± 1.06 mg GA g−1 DW), while the lowest TPC content was found in cardamom water extract (1.04 ± 0.29 mg GA g−1 DW). The AA evaluated by two different assays (ferric-reducing antioxidant power-FRAP and the scavenging activity of the cationic ABTS radical) proved that galangal rhizome is the plant with the highest antioxidant potential. In addition, no statistical difference was found between the AA of turmeric and ginger extracts, while cardamom rhizome was again inferior. In contrast to the crude extracts, the EOs resulted in significantly lower ABTS and FRAP values, with turmeric EO showing the highest AA.

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“…Carbone, Macchioni, Petrella and Cicero [ 114 ] compared the use of US and MW for the extraction efficiency of bioactive compounds from hop herb ( Humulus lupulus ). They mentioned that MW (2.45 GHz, 2.4 × 10 6 Pa, 210 °C, and 1 min) resulted in a higher extraction power for its phenolic contents (95 mg GAL/g) than US (40 kHz, 25 °C, and 30 min) with 25 mg GAL/g.…”

Section: Critical Analysis Of Us and Other Emerging Technologiesmentioning

confidence: 99%

Recent innovations of ultrasound green technology in herbal phytochemistry: A review

Gouda

Bekhit

Tang

et al. 2021

Ultrasonics Sonochemistry

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Highlights Ultrasound enhances the phenolic compounds in extracted herbal oils by 44%. US (25–50 kHz) increases the yields of polyphenols, carotenoids, and flavonoids. Radicals generated by US have positive and negative effects on enzymes. US improves the efficiency of herbal extracts in Nanotechnology applications. Acoustic-based biosensors could be used for chemical imaging of herbal tissues.

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Exploring the potential of microwaves and ultrasounds in the green extraction of bioactive compounds from Humulus lupulus for the food and pharmaceutical industry

Cited by 53 publications

References 59 publications

A Metabolomic Approach to Beer Characterization

A Metabolomic Approach to Beer Characterization

Comparative Study of Chemical Composition and Antioxidant Activity of Essential Oils and Crude Extracts of Four Characteristic Zingiberaceae Herbs

Recent innovations of ultrasound green technology in herbal phytochemistry: A review

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