We present a novel approach to identify galaxy clusters that are undergoing a merger using a deep learning approach. This paper uses massive galaxy clusters spanning 0 ≤ z ≤ 2 from The Three Hundred project, a suite of hydrodynamic re-simulations of 324 large galaxy clusters. Mock, idealised Compton-y and X-ray maps were constructed for the sample, capturing them out to a radius of 2R200. The idealised nature of these maps mean they do not consider observational effects such as foreground or background astrophysical objects, any spatial resolution limits or restriction on X-ray energy bands. Half of the maps belong to a merging population as defined by a mass increase ΔM/M ≥ 0.75, and the other half serve as a control, relaxed population. We employ a convolutional neural network architecture and train the model to classify clusters into one of the groups. A best-performing model was able to correctly distinguish between the two populations with a balanced accuracy (BA) and recall of 0.77, ROC-AUC of 0.85, PR-AUC of 0.55 and F1 score of 0.53. Using a multichannel model relative to a single channel model, we obtain a 3% improvement in BA score, and a 6% improvement in F1 score. We use a saliency interpretation approach to discern the regions most important to each classification decision. By analysing radially binned saliency values we find a preference to utilise regions out to larger distances for mergers with respect to non-mergers, greater than ∼1.2R200 and ∼0.7R200 for SZ and X-ray respectively.