Background: The rehabilitation of an individual with mental illness is an evidenced-based approach to reducing the burden of the illness and the associated stigma globally. Specifically, in Africa, it has promising value for African life and the African economy. Psychosocial rehabilitation is described as a set of approaches that aim to assist an individual in achieving restoration from a state of dependency caused by schizophrenia to a state of being an independent decision-maker. However, there seems to be a dearth of literature and implementation of psychosocial rehabilitation in Africa. Therefore, it is necessary to map articles on how rehabilitation is conducted for people living with the most chronic form of mental illness, schizophrenia, in Africa.Methods: This study will adopt the Arsey and O’Malley scoping review framework to search and compile relevant articles. This process will involve three steps: title screening, which will be performed solely by the principal investigator, followed by abstract and full-text screening, which will be performed independently by two reviewers (the principal investigator and co-investigator). The data charting form will be used by both reviewers for screening, while Rayyan QCRI, a systematic reviews web app, will be used for tracking the screening records. The quality of articles identified for screening will be assessed by the Mixed Method Appraisal Tool (MMAT), and content analysis of the screened articles will be performed with NVivo.Discussion: This study has the likelihood of revealing a research gap in rehabilitation approaches and methods. The results of the review will constitute part of the available evidence that the researchers aim to adopt in the broader part of the project, which aims to develop implementation strategies for the rehabilitation of chronic mental illnesses, specifically schizophrenia, in Sub-Saharan Africa. The implementation process also encompasses the dissemination of the findings of this review to stakeholders, which will enhance their knowledge of the current state of Sub-Saharan Africa and may stimulate support for the implementation of rehabilitation strategies.