Exploring the research landscape of COVID-19-induced olfactory dysfunction: A bibliometric study

Yang, Zhaohui; Ma, Yukun; Bi, Wei; Tang, Jingqian

doi:10.3389/fnins.2023.1164901

Cited by 6 publications

(6 citation statements)

References 74 publications

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“…To avoid potential bias from the daily updates in Scopus, the documents for this study were retrieved and saved on April 12, 2023. The majority of bibliometric studies use Scopus[ 28 - 32 ] and Web of Knowledge[ 33 - 35 ]. Scopus is regarded as the most advantageous database for such analyses due to its numerous benefits[ 36 - 40 ].…”

Section: Methodsmentioning

confidence: 99%

Global research trends and mapping knowledge structure of depression in dialysis patients

Al-Jabi¹

2023

World J Psychiatry

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Rapid-cycling bipolar disorder (RCBD) is a phase of bipolar disorder defined by the presence of ≥ 4 mood episodes in a year. It is a common phenomenon characterized by greater severity, a predominance of depression, higher levels of disability, and poorer overall outcomes. It is resistant to treatment by conventional pharmacotherapy. The existing literature underlines the scarcity of evidence and the gaps in knowledge about the optimal treatment strategies for RCBD. However, most reviews have considered only pharmacological treatment options for RCBD. Given the treatment-refractory nature of RCBD, nonpharmacological interventions could augment medications but have not been adequately examined. This review carried out an updated and comprehensive search for evidence regarding the role of nonpharmacological therapies as adjuncts to medications in RCBD. We identified 83 reviews and meta-analyses concerning the treatment of RCBD. Additionally, we found 42 reports on adjunctive nonpharmacological treatments in RCBD. Most of the evidence favoured concomitant electroconvulsive therapy as an acute and maintenance treatment. There was preliminary evidence to suggest that chronotherapeutic treatments can provide better outcomes when combined with medications. The research on adjunctive psychotherapy was particularly scarce but suggested that psychoeducation, cognitive behavioural therapy, family interventions, and supportive psychotherapy may be helpful. The overall quality of evidence was poor and suffered from several methodological shortcomings. There is a need for more methodologically sound research in this area, although clinicians can use the existing evidence to select and individualize nonpharmacological treatment options for better management of RCBD. Patient summaries are included to highlight some of the issues concerning the implementation of adjunctive nonpharmacological treatments.

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Section: Methodsmentioning

confidence: 99%

Global research trends and mapping knowledge structure of depression in dialysis patients

Al-Jabi¹

2023

World J Psychiatry

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“…One of the notable sequelae of Long COVID-19 is olfactory dysfunction (OD), which can last for months after the initial SARS-CoV-2 infection [15][16][17]. The precise mechanisms underlying the development of OD in Long COVID are not yet fully understood, but several hypotheses have been proposed [18,41]. Persistent viral infection or reactivation within the olfactory system may lead to chronic inflammation and damage to the olfactory neurons or supporting cells [42,43].…”

Section: Od In Long-covid-19mentioning

confidence: 99%

“…This is primarily due to a shortage of robust evidence in the literature, a consequence of insufficient research funding, inadequate participant numbers, and methodological diversity that hampers the generalizability of study outcomes. The urgency imposed by the pandemic has, however, catalyzed research efforts and funding toward developing treatments for OD [18]. Current treatment recommendations for OD include the administration of systemic and intranasal corticosteroids, particularly for inflammatory conditions such as chronic rhinosinusitis (CRS) and severe allergic rhinitis [19].…”

Section: Introductionmentioning

confidence: 99%

Platelet-Rich Plasma (PRP) in the Treatment of Long COVID Olfactory Disorders: A Comprehensive Review

Maniaci,

Lavalle,

Masiello

et al. 2024

Biomedicines

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Background: Long COVID has brought numerous challenges to healthcare, with olfactory dysfunction (OD) being a particularly distressing outcome for many patients. The persistent loss of smell significantly diminishes the affected individual’s quality of life. Recent attention has been drawn to the potential of platelet-rich plasma (PRP) therapy as a treatment for OD. This comprehensive review aims to evaluate the effectiveness of PRP therapy in ameliorating OD, especially when associated with long-term COVID-19. Methods: We executed a comprehensive search of the literature, encompassing clinical trials and observational studies that utilized PRP in treating OD limited to COVID-19. We retrieved and comprehensively discussed data such as design, participant demographics, and reported outcomes, focusing on the efficacy and safety of PRP therapy for OD in COVID-19 patients. Results: Our comprehensive analysis interestingly found promising perspectives for PRP in OD following COVID-19 infection. The collective data indicate that PRP therapy contributed to a significant improvement in olfactory function after COVID-19 infection. Conclusions: The evidence amassed suggests that PRP is a promising and safe therapeutic option for OD, including cases attributable to Long COVID-19. The observed uniform enhancement of olfactory function in patients receiving PRP highlights the necessity for well-designed, controlled trials. Such studies would help to refine treatment protocols and more definitively ascertain the efficacy of PRP in a broader, more varied patient cohort.

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“…Therefore, the primary objective of this study is to adapt and validate the Italian version of the QOD (IT-QOD), in order to provide a reliable tool to assess Italian patients with olfactory dysfunction. This endeavour is of particular importance considering that, in recent years, Italy has ranked second among countries worldwide in terms of the number of research articles produced on olfactory disorders 18 .…”

Section: Introductionmentioning

confidence: 99%

Validity and reliability of the Questionnaire of Olfactory Disorders for Italian-speaking patients with olfactory dysfunction

Vaira,

Tirelli,

Rizzo

et al. 2024

Acta Otorhinolaryngol Ital

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SUMMARY Objective To translate and validate an Italian version of the Questionnaire of Olfactory Disorders (IT-QOD). Materials and methods This is a prospective, multicentre study that involved patients with olfactory dysfunction (OD). Both cases and controls underwent administration of the IT-QOD, Sino-Nasal Outcome Test-22 (SNOT-22) and psychophysical evaluation of orthonasal and retronasal olfactory function. Results The IT-QOD was administered to 96 patients and 38 controls. The Cronbach’s alpha exceeded 0.90, indicating satisfactory internal consistency. The test-retest reliability was found to be high for both parosmia (rs = 0.944) and life quality (rs = 0.969). Patients with OD had significantly higher IT-QOD scores compared to healthy individuals (p < 0.001), indicating strong internal validity. The external validity was also satisfactory, as shown by the significant correlation with SNOT-22 (rs = -0.54) and the threshold, discrimination, and identification score (rs = -0.63). Conclusions The IT-QOD was demonstrated to be reliable and valid to assess the impact of OD on the quality of life of Italian-speaking patients.

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Exploring the research landscape of COVID-19-induced olfactory dysfunction: A bibliometric study

Cited by 6 publications

References 74 publications

Global research trends and mapping knowledge structure of depression in dialysis patients

Global research trends and mapping knowledge structure of depression in dialysis patients

Platelet-Rich Plasma (PRP) in the Treatment of Long COVID Olfactory Disorders: A Comprehensive Review

Validity and reliability of the Questionnaire of Olfactory Disorders for Italian-speaking patients with olfactory dysfunction

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