Abstract:Multiple sclerosis (MS) is a chronic inflammatory and
neurodegenerative
disease of the central nervous system (CNS). Although emerging evidence
has shown that changes in neurotransmitter levels in the synaptic
gap may contribute to the pathophysiology of MS, their specific role
has not been elucidated yet. In this review, we aim to analyze preclinical
and clinical evidence on the structural and functional changes in
neurotransmitters in MS and critically discuss their potential role
in MS pathophysiology. Prec… Show more
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