Exploring the therapeutic potential of defective interfering particles in reducing the replication of SARS-CoV-2
Macauley Locke,
Dmitry Grebennikov,
Igor Sazonov
et al.
Abstract:SARS-CoV-2 still presents a global threat to human health due to the continued emergence of new strains and waning immunity amongst vaccinated populations. Therefore, it is still relevant to investigate potential therapeutics, such as therapeutic interfering particles (TIPs). Mathematical and computational modelling are valuable tools to study viral infection dynamics for predictive analysis. Here, we expand on the previous work by Grebennikov et al. (2021) on SARS-CoV-2 intra-cellular replication dynamics to … Show more
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