Exploring Untouched Variant of Bis(2‐methyl‐1H‐indol‐3‐yl)methane: Enhances Chemo and Mono‐Selectivity

Abstract

The new derivatives of bis(2‐methyl‐1H‐indol‐3‐yl)methane are synthesized by employing decanoic acid to boost aldehyde reactivity via electrophilic activation. The reactions entail combining 2‐methyl‐1H‐indole with various aromatic, aliphatic, and heterocyclic aldehydes at room temperature for 24 h. The newly synthesized compound 4‐(bis(2‐methyl‐1H‐indol‐3‐yl)methyl)‐3‐bromophenol f) has been characterized through 2D structure elucidation. Chemo selectivity and mono selectivity have been explored.