Exponential error reduction in pretransfusion testing with automation

South, Susan F.; Casina, Tony S.; Li, Lily

doi:10.1111/j.1537-2995.2012.03816.x

Cited by 20 publications

(17 citation statements)

References 4 publications

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“…Automation is becoming essential for transfusion centers. Introduction of increasingly automated instruments for immunohematology testing is leading to dramatic progression in blood transfusion efficiency and safety by reducing error potentials, guaranteeing reliable traceability, minimizing workload, and lowering costs . An effective move from manual methods to automation can be achieved with relatively little training …”

mentioning

confidence: 99%

A multicenter study on the performance of a fully automated, walk‐away high‐throughput analyzer for pretransfusion testing in the US population

Roback

Barclay

Moulds³

et al. 2015

Transfusion

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mentioning

confidence: 99%

A multicenter study on the performance of a fully automated, walk‐away high‐throughput analyzer for pretransfusion testing in the US population

Roback

Barclay

Moulds³

et al. 2015

Transfusion

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“…This can prevent human errors on labelling of tube/plate, pipetting, result reading, interpretation, transcription, etc., from happening. A study by South et al provided quantitative evidence on how automation could transform pretransfusion testing processes by dramatically reducing error potentials and thus would improve the safety of blood transfusion [44]. The latest BCSH guideline (2012) for pretransfusion compatibility procedures recommended that fully automated systems should be used wherever possible to reduce the risks of interpretation and transcription errors [20].…”

Section: How Can Information Technology Help In Minimizing Human Erromentioning

confidence: 99%

Using information technology to eliminate wrong blood transfusions

Chu

Cheng

2015

ISBT Science Series

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Advances in the last three decades have dramatically improved blood safety, and wrong blood transfusion (mistransfusion) has now became the most important serious hazards of blood transfusion. The application of information technology in minimizing mistransfusion has further enhanced transfusion safety through the reduction of human steps that are prone to errors. Electronic bedside identification system using hand-held computer and portable printer will minimize the risk of mistransfusion caused by blood sampling error for compatibility testing and patient identification error before blood administration. Fully automated blood bank immunohaematology testing systems together with laboratory information system (LIS) would minimize blood bank errors. Remote electronic blood release system can be considered an extension of the blood bank LIS to the point of care in ensuring the safe release of computer cross-match-compatible blood. Computer physician order entry (CPOE) would guide physicians in making appropriate requests, and connectivity with clinical data repository and blood bank LIS would provide clinical decision support and thus help to prevent human errors.

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“…Human error during manual pre‐transfusion testing has dramatic consequences for patients, causing transfusion‐related adverse events and, in extreme cases, leading to death (South et al ., ). Therefore, high priority should be given to promoting safe and appropriate transfusion practice in blood transfusion laboratories.…”

mentioning

confidence: 97%

Multicentre evaluation of Erytra Eflexis®, a benchtop fully automated analyser with a compact design for routine use in blood transfusion laboratory

Elliott

Carrascosa

Souchet

et al. 2019

Transfusion Medicine

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Objectives: Evaluation of the compact benchtop Erytra Eflexis ® automated analyser was performed at three health centres representing a range of routine transfusion workload.Background: Automation instruments with the simplicity and flexibility adequate for small-to mid-sized blood transfusion services are an unmet need. Methods: Performance in pre-transfusion testing (2109 ABO/D, 382 Rh/K phenotype, 2001 antibody screening, 113 antibody identification, 151 DAT, 88 extended phenotype; 655 cross matching) in comparison to Erytra ® as reference device was assessed. Throughput [time to first result (TTFR), final turn-around time (TAT), processing rate] was calculated; usability and adaptability in laboratory practice under routine and with emergency samples were surveyed.Results: Agreement between systems was 99·8% (11/5499 test discrepancies, all due to weak/doubtful positive reactions). Erytra Eflexis produced six true positives (two Rh/D, two B positives, two screening), four false positives (three screening and one cross matching) and one false negative (screening). Processing of eight routine samples with the Erytra Eflexis for ABO/Rh(D) and screening took 34-38 min and 32-37 min, respectively, independent of the simultaneous processing of a STAT sample, whether or not the incubator for STAT was reserved. In this scenario, a STAT sample requested within 2 min after the routine load was processed in 14-26 min. Processing rate tended to stabilise and optimise in the larger workloads, particularly in ABO/Rh(D)/K cards (16·7, 18 and 19·5 results/h for 10, 15 and 24 specimens, respectively). Conclusion:Erytra Eflexis analyser was found to be reliable and suitable for pre-transfusion routine tests performed in a small-/medium-sized blood transfusion laboratory.

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Exponential error reduction in pretransfusion testing with automation

Abstract: This study provided quantitative evidence on how automation could transform pretransfusion testing processes by dramatically reducing error potentials and thus would improve the safety of blood transfusion.

Cited by 20 publications

References 4 publications

A multicenter study on the performance of a fully automated, walk‐away high‐throughput analyzer for pretransfusion testing in the US population

A multicenter study on the performance of a fully automated, walk‐away high‐throughput analyzer for pretransfusion testing in the US population

Using information technology to eliminate wrong blood transfusions

Multicentre evaluation of Erytra Eflexis®, a benchtop fully automated analyser with a compact design for routine use in blood transfusion laboratory

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