Exportin-inspired artificial cell nuclear-exporting nanosystems

Inui, Mitsuo; Hamada, Yuta; Sejima, Nana; Ueda, Natsumi; Katayama, Tokitaka; Ono, Kimika; Nagahama, Koji

doi:10.1039/d2na00050d

Nanoscale Adv.

2022

DOI: 10.1039/d2na00050d

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Exportin-inspired artificial cell nuclear-exporting nanosystems

Mitsuo Inui¹,

Yuta Hamada²,

Nana Sejima³

et al.

Abstract: The abnormal accumulation of biomolecules and drugs in the cell nucleus causes various types of diseases and side effects, highlighting the need to develop artificial nuclear-exporting technologies, yet there are...

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Advancing Biomolecule Delivery in Plants: Harnessing Synthetic Nanocarriers to Overcome Multiscale Barriers for Cutting-Edge Plant Bioengineering

Miyamoto,

Numata

2023

Bulletin of the Chemical Society of Japan

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The delivery of functional biomolecules, including DNA, RNA, and proteins, into plants presents a unique opportunity to manipulate plant traits and address challenges related to global food security and environmental issues. However, the current methods of biomolecule delivery in plants face various limitations, such as dependence on specific plant species, low delivery efficiency, and complex procedures. In this context, nanocarriers have emerged as promising systems for biomolecule delivery, harnessing the power of chemistry and nanotechnology to overcome these limitations. They offer new possibilities for plant-related research and have the potential to revolutionize plant bioengineering. This review aims to provide a comprehensive overview of the current state of nanocarrier-mediated biomolecule delivery within plants. It highlights strategies to overcome the biological barriers encountered in plants and discusses the future directions for nanocarrier design and application, expanding the scope of plant bioengineering.

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Advancing Biomolecule Delivery in Plants: Harnessing Synthetic Nanocarriers to Overcome Multiscale Barriers for Cutting-Edge Plant Bioengineering

Miyamoto,

Numata

2023

Bulletin of the Chemical Society of Japan

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Exportin-inspired artificial cell nuclear-exporting nanosystems

Abstract: The abnormal accumulation of biomolecules and drugs in the cell nucleus causes various types of diseases and side effects, highlighting the need to develop artificial nuclear-exporting technologies, yet there are...

Cited by 1 publication

References 31 publications

Advancing Biomolecule Delivery in Plants: Harnessing Synthetic Nanocarriers to Overcome Multiscale Barriers for Cutting-Edge Plant Bioengineering

Advancing Biomolecule Delivery in Plants: Harnessing Synthetic Nanocarriers to Overcome Multiscale Barriers for Cutting-Edge Plant Bioengineering

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