Increasing water consumption and climate change are putting countries all over the world at risk of running out of water supply. The provision of groundwater helped reduce global food scarcity, but overexploitation resulted in the depletion of groundwater resources in many regions worldwide. In this study, the concept of reliability, resiliency and vulnerability has been applied to determine the spatial distribution of sustainability in groundwater resources over the intensive groundwater irrigated region of South Asia and China. The satellite-based Global Land Data Assimilation System (GLDAS) data of groundwater storage for 2003-2020 were acquired and used for this reason. The ndings showed a decrease in groundwater storage in Northern China, Western India, and Eastern Pakistan, with the highest declination rate in western India by -50 to -200 mm per decade. The groundwater reliability, resiliency and vulnerability were noticed to decrease in some regions of the study area, with the highest decrease in west India by -0.2 to -0.3 per decade. This caused a decrease in groundwater sustainability in the area at a rate of -0.1 to -0.3 per decade. The reduction in groundwater sustainability in western India may be due to intensive groundwater abstraction in those regions.