Exposed zebrafish (Danio rerio) to imidazolium-based ionic liquids with different anions and alkyl-chain lengths

Zhang, Cheng; Du, Zhongkun; Wang, Jinhua; Wang, Jun; Zhou, Tongtong; Li, Bing; Zhu, Lusheng; Li, Wenxiu; Hou, Kaixuan

doi:10.1016/j.chemosphere.2018.03.178

Cited by 35 publications

(9 citation statements)

References 36 publications

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“…SOD and CAT, as the main antioxidant enzymes, play an important role in resisting oxidative stress [ 34 ]. While SOD uses free radicals as a substrate, converting O 2− to H 2 O 2 and O 2 and playing a dominant role in ROS clearance, CAT continuously converts H 2 O 2 to H 2 O and O 2 , finally realizing the function of antioxidant damage [ 36 ]. Organisms exposed to pollutants usually respond by activating antioxidant enzyme activity.…”

Section: Discussionmentioning

confidence: 99%

Immunotoxicity and Transcriptome Analyses of Zebrafish (Danio rerio) Embryos Exposed to 6:2 FTSA

Zhang

Ren

Chen

2023

Toxics

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As a new alternative to perfluorooctane sulfonic acid (PFOS), 6:2 fluorotelomer sulfonic acid (6:2 FTSA) has been widely produced and used in recent years, and its concentration and frequency of detection in the aquatic environment and aquatic organisms are increasing. However, studies of its toxicity in aquatic biological systems are alarmingly scarce, and the relevant toxicological information needs to be improved. In this study, we investigated AB wild-type zebrafish (Danio rerio) embryos subjected to acute 6:2 FTSA exposure for immunotoxicity using immunoassays and transcriptomics. Immune indexes showed significant decreases in SOD and LZM activities, but no significant change in NO content. Other indexes (TNOS, iNOS, ACP, AKP activities, and MDA, IL-1β, TNF-α, NF-κB, TLR4 content) all showed significant increases. These results indicated that 6:2 FTSA induced oxidative stress and inflammatory responses in zebrafish embryos and exhibited immunotoxicity. Consistently, transcriptomics showed that genes involved in the MAPK, TLR and NOD-like receptor signaling pathways (hsp70, hsp701, stat1b, irf3, cxcl8b, map3k8, il1b, tnfa and nfkb) were significantly upregulated after 6:2 FTSA exposure, suggesting that 6:2 FTSA might induce immunotoxicity in zebrafish embryos through the TLR/NOD-MAPK pathway. The results of this study indicate that the safety of 6:2 FTSA should be examined further.

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Section: Discussionmentioning

confidence: 99%

Immunotoxicity and Transcriptome Analyses of Zebrafish (Danio rerio) Embryos Exposed to 6:2 FTSA

Zhang

Ren

Chen

2023

Toxics

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“…The water temperature was maintained at 25 ± 1 °C, and the pH value of the water was between 7.4 and 8.5; the light time in the laboratory was 12 h. The water was fed regularly every day, half of the water was replaced every 2 days, and the excess bait and feces were removed by siphon tubes. Zebrafish were not fed for 24 h prior to the formal experiments, and the zebrafish used for the experiments were randomly selected healthy zebrafish of uniform size. , The LC 50 of the pollutants to zebrafish was mainly determined to provide toxicological data about the acute toxicity of the pollutants.…”

Section: Methodsmentioning

confidence: 99%

“…Zebrafish were not fed for 24 h prior to the formal experiments, and the zebrafish used for the experiments were randomly selected healthy zebrafish of uniform size. 21,22 The LC 50 of the pollutants to zebrafish was mainly determined to provide toxicological data about the acute toxicity of the pollutants.…”

Section: ■ Materials and Methodsmentioning

confidence: 99%

Tribological Properties and Biotoxicity of Gluconate-Based Ionic Liquids as Glycerol Lubricant Additives

Li,

Wang,

Liu

et al. 2024

ACS Sustainable Chem. Eng.

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With increasing environmental awareness and a growing emphasis on green practices, water-based lubricants have gained significant traction in the lubrication industry. In this study, we incorporated a synthesized environmentally friendly and biodegradable gluconate ionic liquid (ILs), [OMIm][gluconate], into a glycerol. The tribological properties of [OMIm][gluconate] as a water-based lubricant additive were comprehensively investigated. Compared with glycerol, the results of the study showed that the friction coefficient and wear volume of the dispersions were reduced by 38.9% and 97.2%, respectively. In addition, [OMIm][gluconate] has excellent tribological properties, significant antimicrobial properties, and low toxicity to animals. The excellent tribological properties of [OMIm][gluconate] are attributed to the tribologically active element N in the molecular structure of ILs to the surface of the friction pair during the friction process. At the same time, a physicochemical adsorption process occurs at the interface of the additive molecules with the friction pair and a complex tribochemical took place. This process culminates in the formation of a highly durable tribofilm, contributing to the material's exceptional toughness. Furthermore, the outstanding antimicrobial properties can be attributed to certain lipid-soluble carbon chain structures that disrupt the integrity of bacteria, leading to the effective eradication of Escherichia coli.

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“…ILs are widely used solvents for CO 2 capture, but the majority of them have been prepared or based on imidazole or pyridine functional groups, which have a non-negligible biological toxic effect. [301][302][303] Though DES is a promising breakthrough in this prospect, DES-based CO 2 capture needs to be improved for scaling up on an industrial scale. Thus, the exploration of DES in CO 2 adsorption, membrane separation, and catalytic conversion, to develop a more environment friendly CCU process, is crucial.…”

Section: Challenges and Progress Of The Il/co 2 Systemmentioning

confidence: 99%

Integrated CO₂capture and electrochemical upgradation: the underpinning mechanism and techno-chemical analysis

De¹,

Won

Kim

et al. 2023

Chem. Soc. Rev.

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Exposed zebrafish (Danio rerio) to imidazolium-based ionic liquids with different anions and alkyl-chain lengths

Cited by 35 publications

References 36 publications

Immunotoxicity and Transcriptome Analyses of Zebrafish (Danio rerio) Embryos Exposed to 6:2 FTSA

Immunotoxicity and Transcriptome Analyses of Zebrafish (Danio rerio) Embryos Exposed to 6:2 FTSA

Tribological Properties and Biotoxicity of Gluconate-Based Ionic Liquids as Glycerol Lubricant Additives

Integrated CO₂capture and electrochemical upgradation: the underpinning mechanism and techno-chemical analysis

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Exposed zebrafish (Danio rerio) to imidazolium-based ionic liquids with different anions and alkyl-chain lengths

Cited by 35 publications

References 36 publications

Immunotoxicity and Transcriptome Analyses of Zebrafish (Danio rerio) Embryos Exposed to 6:2 FTSA

Immunotoxicity and Transcriptome Analyses of Zebrafish (Danio rerio) Embryos Exposed to 6:2 FTSA

Tribological Properties and Biotoxicity of Gluconate-Based Ionic Liquids as Glycerol Lubricant Additives

Integrated CO2capture and electrochemical upgradation: the underpinning mechanism and techno-chemical analysis

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Product

Resources

About

Integrated CO₂capture and electrochemical upgradation: the underpinning mechanism and techno-chemical analysis