2003
DOI: 10.1590/s0021-75572003000600010
|View full text |Cite
|
Sign up to set email alerts
|

Exposição aguda a derivados imidazolínicos em crianças

Abstract: Most children (especially those younger than 3 years) exposed to imidazoline derivatives (especially naphazoline) presented early signs of poisoning regardless of the exposure route (nasal or oral). The main signs observed were nervous system, cardiovascular and respiratory depression. Most children showed complete resolution of the symptoms within 24 hours.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
4
0
5

Year Published

2005
2005
2021
2021

Publication Types

Select...
7

Relationship

2
5

Authors

Journals

citations
Cited by 11 publications
(9 citation statements)
references
References 11 publications
0
4
0
5
Order By: Relevance
“…21 In fact, there is no consensus regarding the dosage or duration of treatment with topical nasal decongestants, including those that can be purchased without a prescription (except for those containing vasoconstrictors). 22 These factors may result in an increase in the number of times the IDDD contacts the nasal vestibule and raises the possibility of contamination and/or recontamination, increasing the risk to users.…”
Section: Discussionmentioning
confidence: 99%
“…21 In fact, there is no consensus regarding the dosage or duration of treatment with topical nasal decongestants, including those that can be purchased without a prescription (except for those containing vasoconstrictors). 22 These factors may result in an increase in the number of times the IDDD contacts the nasal vestibule and raises the possibility of contamination and/or recontamination, increasing the risk to users.…”
Section: Discussionmentioning
confidence: 99%
“…Similar cases evolve favorably within the first 24 hours without the need for invasive procedures, with improvement in episodes of apnea and bradycardia after intermittent tactile stimulation. 23,24 In fatal case 4, clinical manifestations and severe hypoglycemia at admission suggest that an oral hypoglycemic intake may also have occurred. 25 Impaction of button batteries in esophageal lumen can lead to high morbidity, including lethal outcomes.…”
Section: Prolonged Parenteral Nutritionmentioning
confidence: 99%
“…[42][43] AAPCC-TESS data (1993)(1994)(1995)(1996)(1997)(1998)(1999) show a significant increase in clonidine exposure in children, related to an increase in the prescription of this drug for the management of attention deficit hyperactivity d i s o r d e r . 4 2 C l o n i d i n e p o i s o n i n g c a u s e s c l i n i c a l m a n i f e s t a t i o n s t h a t r e s e m b l e t h o s e o f t o p i c a l decongestants containing imidazoline derivatives, 44 with rapid onset of action, 30 to 60 minutes after exposure. 9,42 Common clinical signs in children include central nervous system depression, hypothermia, bradycardia, miosis, and respiratory depression, which develop when a dose of clonidine greater than 10 µg/kg is ingested.…”
Section: Naloxonementioning
confidence: 99%
“…9 Treatment is based on supportive care. 9,42,44 Naloxone has been empirically used and no controlled studies exist that support its use. 9,[42][43] Flumazenil Benzodiazepines are among the most widely prescribed drugs around the world and are the major cause of toxic exposure to medications in our setting.…”
Section: Naloxonementioning
confidence: 99%