Exposure assessment of aflatoxins and zearalenone in edible vegetable oils in Shandong, China: health risks posed by mycotoxin immunotoxicity and reproductive toxicity in children

Li, Fenghua; Zhao, Xianqi; Yang, Jiao; Duan, Xinglan; Yu, Lianlong; Zheng, Fengjia; Wang, Xiaolin; Wang, Lin; Wang, Jiasheng; Zhao, Xiaozhen; Zhang, Tianliang; Li, Wei; Zha, Jun

doi:10.1007/s11356-022-22385-2

Cited by 17 publications

(7 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…By contrast, the DON contaminations less than 100 µg/kg were found in Qingdao, Heze, Zaozhuang, Zibo, Dongying, Jining and Jinan. Of note, Jinan city as the capital city of the Shandong, maintained very low mycotoxin contamination in foods in this study and the other studies by our laboratories (Li, Duan, et al, 2022; Li, Zhao, et al, 2022). 3‐A‐DON and 15‐A‐DON were only found in the four cities of which noodle samples were heavily contaminated (Binzhou, Weihai, Linyi, and Weifang), but their amounts were considerably low.…”

Section: Resultssupporting

confidence: 74%

Mycotoxin monitoring in Shandong province, China reveals health risks for enterohepatic diseases shifted from environment to diet: Deoxynivalenol, zearalenone and nivalenol in noodles (2019–2020)

Duan,

Zhang,

et al. 2023

Cereal Chem

Self Cite

View full text Add to dashboard Cite

Background and ObjectivesHigh levels of deoxynivalenol (DON) contamination in foods can raise health risks for enterohepatic diseases. Here we report our investigation into the trichothecenes (DON, 3‐acetyl‐deoxynivalenol, 15‐acetyl‐deoxynivalenol), zearalenone (ZEA) and nivalenol (NIV) showing in the wheats‐processed noodles in Shandong, China (2019–2020).FindingsThe noodles contamination status of DON in Shandong was closed to that in China in the past 10 years: 4663.9 µg/kg at maximum level, and a range of 57.9–618.8 µg/kg by mean. However, the average levels of DON measured in the noodle samples varied largely by city. Highest levels of DON contamination were found in Binzhou: 709.09 (58.8–3220) µg/kg and Weihai: 684.79 (27.6–3850) µg/kg, respectively. Besides, NIV contamination were averagely 46.99 µg/kg in Binzhou, and ZEA contamination up to 31.4 µg/kg in Weihai, pose an increasing threat of liver/intestine inflammation associated with dietary exposure.ConclusionsThe DON contamination status of noodles in Shandong was consistent with our previous investigation in wheats and in recent 10 years in China, that increased health risks for enterohepatic diseases.Significance and NoveltyTo understand the contamination situation of DON, ZEA, and NIV in noodles, so as to assess the health risks for enterohepatic diseases caused by mycotoxin in Shandong province.

show abstract

Section: Resultssupporting

confidence: 74%

Mycotoxin monitoring in Shandong province, China reveals health risks for enterohepatic diseases shifted from environment to diet: Deoxynivalenol, zearalenone and nivalenol in noodles (2019–2020)

Duan,

Zhang,

et al. 2023

Cereal Chem

Self Cite

View full text Add to dashboard Cite

show abstract

“…Mycotoxins contribute to yield losses and alter the physical quality of grains. The studies of Baker et al (2006), Inderbitzin et al (2010), Zain (2011), Assunção et al (2016), Lee and Ryu (2017), El‐Sayed et al (2022), Gao et al (2022), Li et al (2022), and Sumarah (2022) support this statement because they all showed that SCLB is associated with mycotoxin production.…”

Section: Resultsmentioning

confidence: 90%

“…Mycotoxins contribute to yield losses and alter the physical quality of grains. The studies ofBaker et al (2006),Inderbitzin et al (2010),Zain (2011), Assunção et al (2016,Lee and Ryu (2017), El-Sayed et al (2022),Gao et al (2022),Li et al (2022),…”

mentioning

confidence: 99%

Rapid screening for resistance of maize inbred and hybrid lines against southern corn leaf blight

Shukuru,

Archana,

Kangela

2023

Journal of Phytopathology

View full text Add to dashboard Cite

Bipolaris is one of the most important phytopathogenic fungal genera to cause disease in cereal crops. Southern corn leaf blight (SCLB) is a pandemic and widespread disease; it's found everywhere corn is grown, causing a noticeable reduction in crop yield. Most cultivated varieties of maize do not resist SCLB disease where it is reported. Nevertheless, previous researchers have reported some resistant varieties of maize. In this study, we tested inbred and hybrid lines collected from ICAR‐IIMR based in Ludhiana against the disease. The field experiment was setup using a Randomized Block Design with three replications in natural conditions. Here we evaluated lines by quantifying disease pressure, yield, and their attributes. Moreover, model‐based clustering allowed the identification of five groups. For the SCLB disease confirmation, infected maize leaves were collected and used for pathogen isolation, and a pure culture was maintained. Both disease assessment and data analysis focused more specifically on characters that showed significant differences between means, especially leaf area, percentage of leaf infection, disease incidence, disease severity, disease index by plot basis, number of grain rows formed per ear, weight of maize kernels per ear, each corn ear weight, shelling percentage, and grain yield. The two best clusters identified, namely Group 1 and Group 2, together comprise 11002, 11009, 11026, 11030, 11069, 11149, 11153, 11185, 11328, 11333, 11337, 11347, 11370, 11385, 11074, 11351, 11356, 11357, 11608, and Karav‐8523 lines. As per disease reaction, CM‐500 is individually one of the best lines in terms of SCLB resistance. Specific symptoms were clearly found on leaves, and pseudo‐septate conidia were observed under the microscope. Thus, several lines exhibited highly resistant reactions against SCLB, especially 11002, 11009, 11026, 11069, 11074, 11337, 11347, 11385, and CM‐500, and can still be recommended for farmers and in breeding programmes, for future usefulness as industries are complaining of maize shortages, and they present a great commercial potential.

show abstract

“…Alternaria toxins such as alternariol and alternariol 9-methyl ether, derived from filamentous fungi of the Alternaria genus, exhibit endocrine-disrupting potential as estrogen receptor agonists [ 19 ] and may also activate other steroid receptors, such as the androgen and progesterone receptors. Ochratoxins, aflatoxin and patulin are other important mycotoxins produced by Aspergillus species and their endocrine-disrupting activity has been analyzed [ 54 , 55 ].…”

Section: Discussionmentioning

confidence: 99%

“…According to reports, it has been observed that some embryos did not develop properly or were malformed [ 17 ]. In addition, an increase in fetal death [ 55 ] and potential impairment in growth [ 31 ] and genital development [ 31 ] and low birth weight [ 54 ] have been observed in association with maternal intake of PEs. Szuckiewitz et al found that genistein may interfere with placental growth factor (PlGF) signaling, which can disrupt fetoplacental growth.…”

Section: Discussionmentioning

confidence: 99%

Toxicological Effects of Naturally Occurring Endocrine Disruptors on Various Human Health Targets: A Rapid Review

Virtuoso,

Raggi,

Maugliani

et al. 2024

Toxics

View full text Add to dashboard Cite

Endocrine-disrupting compounds are chemicals that alter the normal functioning of the endocrine system of living organisms. They can be natural (N-EDCs) or synthetic compounds (S-EDCs). N-EDCs can belong to different groups, such as phytoestrogens (PEs), including flavonoids, or mycotoxins originating from plants or fungi, and cyanotoxins, derived from bacteria. Humans encounter these substances in their daily lives. The aim of this rapid review (RR) is to provide a fine mapping of N-EDCs and their toxicological effects on human health in terms of various medical conditions or adverse consequences. This work is based on an extensive literature search and follows a rigorous step-by-step approach (search strategy, analysis strategy and data extraction), to select eligible papers published between 2019 and 2023 in the PubMed database, and to define a set of aspects characterizing N-EDCs and the different human target systems. Of the N-EDCs identified in this RR, flavonoids are the most representative class. Male and female reproductive systems were the targets most affected by N-EDCs, followed by the endocrine, nervous, bone and cardiovascular systems. In addition, the perinatal, pubertal and pregnancy periods were found to be particularly susceptible to natural endocrine disruptors. Considering their current daily use, more toxicological research on N-EDCs is required.

show abstract

Exposure assessment of aflatoxins and zearalenone in edible vegetable oils in Shandong, China: health risks posed by mycotoxin immunotoxicity and reproductive toxicity in children

Cited by 17 publications

References 57 publications

Mycotoxin monitoring in Shandong province, China reveals health risks for enterohepatic diseases shifted from environment to diet: Deoxynivalenol, zearalenone and nivalenol in noodles (2019–2020)

Mycotoxin monitoring in Shandong province, China reveals health risks for enterohepatic diseases shifted from environment to diet: Deoxynivalenol, zearalenone and nivalenol in noodles (2019–2020)

Rapid screening for resistance of maize inbred and hybrid lines against southern corn leaf blight

Toxicological Effects of Naturally Occurring Endocrine Disruptors on Various Human Health Targets: A Rapid Review

Contact Info

Product

Resources

About