Exposure of children and adolescents from Northeastern Slovenia to per- and polyfluoroalkyl substances

Runkel, Agneta A.; Stajnko, Anja; Tratnik, Janja Snoj; Mazej, Darja; Horvat, Milena; Příbylová, Petra; Kosjek, Tina

doi:10.1016/j.chemosphere.2023.138096

Cited by 1 publication

(1 citation statement)

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“…studies on children include Papadopoulou et al 2016;Koponen et al 2018;, and studies on adults include Kim et al 2014;Bartolomé et al 2017). As a consequence, limited information exists on demographic, life-style and physiological determinants that may explain some of the variation of adolescent body burdens of PFAS (Zhou et al 2016;) with a growing body of literature as this thesis goes to press (Richterová et al 2023;Runkel et al 2023;Sultan et al 2023;Uhl et al 2023). Providing information on important determinants explaining at least some of the variation of PFAS body burdens among adolescents is crucial when identifying important exposure sources, groups with high exposure, and potential confounders in future health studies.…”

Section: Adolescents -An Understudied Populationmentioning

confidence: 99%

Per- and polyfluoroalkyl substances (PFAS) – unravelling exposure sources and demographical exposure patterns in a Swedish adolescent population

Nyström-Kandola

2024

Acta Universitatis Agriculturae Sueciae

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Per- and polyfluoroalkyl acids (PFAS) is a group of anthropogenic substances, with some suspected to cause adverse health effects in humans. Little is known about adolescent exposure to PFAS, thus this thesis focuses on exposure sources and demographical exposure patterns of PFAS in a nationally representative Swedish adolescent (age 10-21 years) population (Riksmaten Adolescents 2016-17). Legacy PFAS, perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA), perfluorohexane sulfonic acid (PFHxS) and perfluorooctane sulfonic acid (PFOS) were detected in serum from 70-100% of the participants (n=1098). Concentrations of PFOA, PFHxS and PFOS in serum increased with increased concentrations in drinking water (DW). Even though median PFAS concentrations in DW were as low as <1 ng/L, DW appeared as an important exposure source. Participants adhering to a diverse and healthy diet had higher PFNA, PFDA, PFUnDA and PFOS concentrations in serum than those that did not. This association was likely driven by a higher seafood consumption as a part of the healthy diet, supporting the notion that diet, apart from DW, is an important exposure source. Serum PFAS levels were on average highest among participants born in countries with high per capita income as compared to those born in low income countries. Conclusively, PFAS are chemicals of the industrialised world, with DW and seafood emerging as important exposure sources for adolescents. The findings of this thesis are important to consider in future risk assessments, as well as in studies of PFAS exposure and adolescent health.

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Section: Adolescents -An Understudied Populationmentioning

confidence: 99%

Per- and polyfluoroalkyl substances (PFAS) – unravelling exposure sources and demographical exposure patterns in a Swedish adolescent population

Nyström-Kandola

2024

Acta Universitatis Agriculturae Sueciae

View full text Add to dashboard Cite

show abstract

Exposure of children and adolescents from Northeastern Slovenia to per- and polyfluoroalkyl substances

Cited by 1 publication

References 52 publications

Per- and polyfluoroalkyl substances (PFAS) – unravelling exposure sources and demographical exposure patterns in a Swedish adolescent population

Per- and polyfluoroalkyl substances (PFAS) – unravelling exposure sources and demographical exposure patterns in a Swedish adolescent population

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