Exposure of <i>Mactra corallina</i> to acute doses of lead: effects on redox status, fatty acid composition and histomorphological aspect

Chetoui, Imene; Bejaoui, Safa; Trabelsi, Wafa; Rabeh, Imen; Nechi, Salwa; Chelbi, Emna; Ghalghaf, Mohamed; Cafsi, Mhamed El; Soudani, Nejla

doi:10.1080/01480545.2019.1693590

Cited by 13 publications

(11 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It plays an important protective role in the damage induced by free radicals scavenging hydroxyls, radicals and singlet oxygen (Tandon et al 2002). The increase in Vit C levels in the digestive gland of R. decussatus from the MCA and the HCA could be due to the crucial role of this antioxidant in protecting the physical status of organisms exposed to TE pollution (Chetoui et al 2019). In line with our data, showed a similar variation in Vit C levels in R. decussatus sampled from the HCA.…”

Section: Discussionsupporting

confidence: 88%

Assessment of oxidative stress, genotoxicity and histopathological responses in the digestive gland of Ruditapes decussatus collected from northern Tunisian lagoons

Bejaoui

Rabeh

Telahigue

et al. 2020

scimar

Self Cite

View full text Add to dashboard Cite

The aim of the present study was to investigate the combined effects of seasonality and anthropogenic pressure on a battery of oxidative stress, lipid peroxidation, protein oxidation, DNA damage and histological alterations in the native clam Ruditapes decussatus collected from a less contaminated area (LCA), Ghar El Melh, a moderately contaminated area (MCA), the North Lake, and a highly contaminated area (HCA), the South Lake, all located in the southern Mediterranean Sea. The accumulation of cadmium, lead, copper, iron and zinc was higher in the digestive glandsof clams collected from the MCA and the HCAthan in those from the LCA, particularly during the warm season. Our results reveal that metallothionein, lipid peroxidation, protein oxidation levels and antioxidant defence systems were higher, while acetylcholinesterase activity was lower, in clams from the MCAand HCAthan in those from the LCA. The results also indicate that clams from the MCA and the HCAare characterized by histological alterations and DNA damage. In conclusion, the evident changes of antioxidant defence systems and macromolecules between the studied lagoons reveal the perturbation of the physiological states of clams from polluted sites thatcope with seasonal changes and trace element accumulations.

show abstract

Section: Discussionsupporting

confidence: 88%

Assessment of oxidative stress, genotoxicity and histopathological responses in the digestive gland of Ruditapes decussatus collected from northern Tunisian lagoons

Bejaoui

Rabeh

Telahigue

et al. 2020

scimar

Self Cite

View full text Add to dashboard Cite

show abstract

“…Our data show lower lipid content in S1 than in S2, which correlates with the increase in the TBARS level mainly in summer. This increase in the TBARS level and decreases in lipid content appears to be due to metal uptake, which accelerates the ability to scavenge ROS by extreme production of lipid peroxides resulting from alteration of membrane fluidity and integrity (Chetoui et al 2019 from contaminated sites on the southwestern Iberian coast (Gomes et al 2013) and the Oued Souss estuary in the Bay of Agadir, Morocco (Ait Alla et al 2006) revealed similar increases in TBARS levels. This may be linked to several factors, including metal concentration (Cd, Pb, etc.…”

Section: Discussionmentioning

confidence: 91%

“…Due to the complex stress responses influenced by metals, metalloids and their mixtures, it is important to create a battery of biomarkers that represent different roles and biological levels, such as the variation of oxidative stress (Di Salvatore et al 2013, Bejaoui et al 2017) and trace element concentration (Di Salvatore et al 2013, Sureda et al 2011, which can be linked to whole-organism responses and ecological responses to indicate the presence of harmful substances in the marine environment (Cravo et al 2012). The toxicity of metals has been attributed mainly to their capacity to increase the generation of reactive oxygen species (ROS), which are thought to be the main cause of lipid and protein peroxidation (Chetoui et al 2019). To neutralize free radicals and counteract the deleterious effects of ROS, cells possess an antioxidant defence system (Halliwell 2007).…”

Section: Introductionmentioning

confidence: 99%

Assessment of trace element accumulation on the Tunisian coasts using biochemical biomarkers in Perinereis cultrifera

Bouhedi

Antit

Chaibi

et al. 2021

scimar

View full text Add to dashboard Cite

Our study aimed to evaluate the effect of trace element pollution in the polychaete Perinereis cultrifera (Grube, 1840) from two Tunisian coasts (the port of Rades, S1; and the Punic port of Carthage, S2). To this end, we used an approach based on proximate composition, biomarker responses and trace element bioaccumulation. Our results showed a decreasing order of metals concentrations (Zn>Cu>Cd>Pb) in P. cultrifera from S1 and S2. The accumulation of Cd, Cu and Zn was significantly higher in S1 than in S2, especially in summer. Lipid, protein and glycogen content also changed significantly between S1 and S2 in relation to trace metal accumulation and environmental conditions. The results revealed a higher level of thiobarbituric acid in P. cultrifera from S1 than from S2. In addition, the enzymatic and non-enzymatic antioxidant defence system (catalase, glutathione-S-transferase, superoxide dismutase, glutathione and metallothionein) was enhanced and acetylcholinesterase activities decreased in P. cultrifera in S1 in comparison with S2. A principal component analysis showed that P. cultrifera from S1 exhibited a clear disruption of oxidative stress responses and trace element bioaccumulation among seasons. Overall, these findings revealed the sensitivity of those organisms to environmental conditions.

show abstract

“…This supposition is highlighted by the high correlation of PUFA, n-3 PUFA, DHA, and EPA with trace elements uptake (r≥ -0.409; p<0.05). Also, this could be attributed to its important role in mediating immunological and in ammatory responses (Thyrring et al 2015;Chetoui et al 2019). Consistent with this, our ndings suggest that TEs uptake could be responsible for the decrease of these processes and may provoke simultaneous modi cations of gills and muscles structure and function via the disruption of their physiological processes.…”

Section: Discussionmentioning

confidence: 99%

Differential Fatty Acids and Stress Biomarkers Responses in Native (Carcinus Aestuarii) and Invasive (Portunus Segnis) Crabs Exposed to Environmental Pollution

Bejaoui

Chetoui

Ghribi

et al. 2021

Preprint

Self Cite

View full text Add to dashboard Cite

The present work aims to determine and compare the tolerance to different stress environmental conditions in two crabs’ species the native Carcinus aestuarii and the invasive Portunus segnis. In this study, C.aestuarii appeared more intolerant to environmental stressor as shown by the important changes occurred on the proximate, fatty acids and their essential compounds comparing to P.segnis. Our results revealed accumulation of metallic trace elements, macromolecular damages and antioxidant defense systems perturbations mostly in C.aesuarii gills and muscles than P.segnis, thus highlighting the importance of a multi-markers approach to assess the urban pollution in coastal ecosystems. According to this study, fatty acid profiles and oxidative stress biomarker examination of both crabs indicate that the different environmental stresses significantly influence the tolerance of C.aestuarii compared to the invasive P.segnis which may provide physiological advantages for the achievement of their invasion in novel ecosystems.

show abstract

Exposure of Mactra corallina to acute doses of lead: effects on redox status, fatty acid composition and histomorphological aspect

Cited by 13 publications

References 66 publications

Assessment of oxidative stress, genotoxicity and histopathological responses in the digestive gland of Ruditapes decussatus collected from northern Tunisian lagoons

Assessment of oxidative stress, genotoxicity and histopathological responses in the digestive gland of Ruditapes decussatus collected from northern Tunisian lagoons

Assessment of trace element accumulation on the Tunisian coasts using biochemical biomarkers in Perinereis cultrifera

Differential Fatty Acids and Stress Biomarkers Responses in Native (Carcinus Aestuarii) and Invasive (Portunus Segnis) Crabs Exposed to Environmental Pollution

Contact Info

Product

Resources

About