Exposure to a Controlled Adverse Environment Impairs the Ocular Surface of Subjects with Minimally Symptomatic Dry Eye

González-García, María J.; Gonzalez–Saiz, A.; Fuente, Beatriz de la; Morilla‐Grasa, Antonio; Mayo-Íscar, Agustín; Alonso, Julio Francisco San José; Feijo, J.; Stern, Michael E.; Calonge, Margarita

doi:10.1167/iovs.06-0817

Cited by 75 publications

(41 citation statements)

References 49 publications

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“…Adverse environmental conditions such as weather that is windy, dry, or low in humidity could lead to reduced tear production, poor tear quality, and/or excessive tear evaporation. 18,26,27 Unstable tear film may contribute to the initiation of pterygium. 28 It should be pointed out that the association between pterygium and dry eye is equivocal.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of and Risk Factors for Pterygium in Rural Adult Chinese Populations of the Bai Nationality in Dali: The Yunnan Minority Eye Study

Zhong

Cha

Tao

et al. 2012

Invest. Ophthalmol. Vis. Sci.

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Section: Discussionmentioning

confidence: 99%

Prevalence of and Risk Factors for Pterygium in Rural Adult Chinese Populations of the Bai Nationality in Dali: The Yunnan Minority Eye Study

Zhong

Cha

Tao

et al. 2012

Invest. Ophthalmol. Vis. Sci.

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“…14,[33][34][35][36][37][38] For this study, we used two types of questionnaires. The SODQ is a seven item symptom-based questionnaire that we used in a previous report 39 and in clinical trials. The SANDE questionnaire 14 is a visual analogue scale based questionnaire.…”

Section: Discussionmentioning

confidence: 99%

Correlations Among Symptoms, Signs, and Clinical Tests in Evaporative-Type Dry Eye Disease Caused by Meibomian Gland Dysfunction (MGD)

Cuevas

González-García²,

Castellanos

et al. 2012

Current Eye Research

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“…To calculate the lysozyme concentration, a standard curve was obtained using identical discs wetted with 10,000, 1,000, 100, and 10 µg/mL of lysozyme (ATCC 4698, L6876; Sigma-Aldrich) diluted in phosphate-buffered saline (Invitrogen Corp., Carlsbad, CA). Values of 1000 µg/mL or below were considered abnormal (19)(20) .…”

Section: Tear Lysozyme Concentrationmentioning

confidence: 99%

Impact of wildfire smoke in Buenos Aires, Argentina, on ocular surface

Berra¹,

Galperín²,

Dawidowski

et al. 2015

Arquivos Brasileiros De Oftalmologia

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Purpose: To evaluate the acute impact of the wildfire smoke episode in 2008 on the ocular surface of subjects living in the Metropolitan Area of Buenos Aires (MABA). Methods: A total of 86 subjects were evaluated: Group 1 comprised patients from a public ophthalmology hospital (N=35) and Group 2 comprised healthy volunteers (N=51). All subjects answered a questionnaire on ocular symptoms and underwent ophthalmologic examination [bulbar conjunctival hyperemia, corneal fluorescein staining, rose bengal vital staining, tear break-up time (TBUT), Schirmer I test, tear lysozyme, and impression cytology] during and after the acute episode. Concentrations of carbon monoxide (CO), nitrogen dioxide (NO 2 ), and particulate matter (PM) were measured before, during, and after the acute episode. Results: Both groups showed a statically significant increase in ocular symptoms and bulbar conjunctival hyperemia and a statically significant decrease in tear break-up time during the acute episode. Group 1 showed more severe symptoms and a statistically significant increase in fluorescein and rose bengal staining intensities during the acute episode. We found a significant negative correlation between ocular symptoms and tear break-up time. During the episode, the levels of CO, NO 2 , and particulate matter in MABA were four times higher than the usual average levels for the same period in 2007 and 2009. Conclusions: Increased air pollution from the burning of biomass is associated with a decrease in the stability of the tear film (TBUT), generating areas of ocular surface exposure that may be the cause of the increased feeling of irritation. Group 1 was more affected by not having a healthy ocular surface, and thus consulted an ophthalmologist. Cytological changes in the conjunctiva were not observed, which could be due to the short duration of the episode.

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Exposure to a Controlled Adverse Environment Impairs the Ocular Surface of Subjects with Minimally Symptomatic Dry Eye

Cited by 75 publications

References 49 publications

Prevalence of and Risk Factors for Pterygium in Rural Adult Chinese Populations of the Bai Nationality in Dali: The Yunnan Minority Eye Study

Prevalence of and Risk Factors for Pterygium in Rural Adult Chinese Populations of the Bai Nationality in Dali: The Yunnan Minority Eye Study

Correlations Among Symptoms, Signs, and Clinical Tests in Evaporative-Type Dry Eye Disease Caused by Meibomian Gland Dysfunction (MGD)

Impact of wildfire smoke in Buenos Aires, Argentina, on ocular surface

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