Exposure to Manganese: Health Effects on the General Population, a Pilot Study in Central Mexico

Santos‐Burgoa, Carlos; Rı́os, Camilo; Mercado, Luis Alberto; Arechiga-Serrano, Rodolfo; Cano-Valle, Fernando; Eden-Wynter, Rocío Alatorre; Texcalac-Sangrador, José Luis; Villa-Barragán, Juan Pablo; Rodríguez-Agudelo, Y.; Montes, Sergio

doi:10.1006/enrs.2000.4108

Cited by 121 publications

(62 citation statements)

References 35 publications

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“…In adults living in Greece, abnormal neurological scores were associated with higher hair and water manganese concentrations (63). SantosBurgoa et al (64) reported a significant inverse association between blood Mn levels and MiniMental Status Exam scores among adults living proximal to a Mn mining district in central Mexico. In Chinese children, exposure to elevated manganese concentrations in drinking water was associated with lower scores on tests of short-term memory, manual dexterity, and visualperceptual speed (65).…”

Section: Neurotoxicity Of Manganesementioning

confidence: 99%

The Challenge Posed to Children's Health by Mixtures of Toxic Waste: The Tar Creek Superfund Site as a Case-Study

Shine²,

Wright

2007

Pediatric Clinics of North America

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Section: Neurotoxicity Of Manganesementioning

confidence: 99%

The Challenge Posed to Children's Health by Mixtures of Toxic Waste: The Tar Creek Superfund Site as a Case-Study

Shine²,

Wright

2007

Pediatric Clinics of North America

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“…Cr (VI) is known to have toxic and carcinogenic effect on the bronchial tree (Manalis et al 2005;Hu 2002). Mn exposure leads to increased neurotoxic impairments (Santos-Burgoa et al 2001). The increased level of Cu can lead to respiratory irritance (ATSDR 2002;Manalis et al 2005).…”

Section: Introductionmentioning

confidence: 99%

Ambient air quality of Lucknow City (India) during use of fireworks on Diwali Festival

Barman

Singh

Negi

et al. 2007

Environ Monit Assess

158

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The present study deals with the effect of fireworks on ambient air quality during Diwali Festival in Lucknow City. In this study, PM(10), SO(2), NO( x ) and 10 trace metals associated with PM(10) were estimated at four representative locations, during day and night times for Pre Diwali (day before Diwali) and Diwali day. On Diwali day 24 h average concentration of PM(10), SO(2), and NO( x ) was found to be 753.3, 139.1, and 107.3 mug m(-3), respectively, and these concentrations were found to be higher at 2.49 and 5.67 times for PM(10), 1.95 and 6.59 times for SO(2) and 1.79 and 2.69 for NO( x ), when compared with the respective concentration of Pre Diwali and normal day, respectively. On Diwali day, 24 h values for PM(10), SO(2), and NO( x ) were found to be higher than prescribed limit of National Ambient Air Quality Standard (NAAQS), and exceptionally high (7.53 times) for PM(10). On Diwali night (12 h) mean level of PM(10), SO(2) and NO( x ) was 1,206.2, 205.4 and 149.0 mug m(-3), respectively, which was 4.02, 2.82 and 2.27 times higher than their respective daytime concentrations and showed strong correlations (p < 0.01) with each other. The 24 h mean concentration of metals associated with PM(10) was found to be in the order of Ca (3,169.44) > Fe (747.23) > Zn (542.62) > Cu (454.03), > Pb (307.54) > Mn (83.90) > Co (78.69) > Cr (42.10) > Ni (41.47) > Cd (34.69) in ng m(-3) and all these values were found to be higher than the Pre Diwali (except Fe) and normal day. The metal concentrations on Diwali day were found to be significantly different than normal day (except Fe & Cu). The concentrations of Co, Ni, Cr and Cd on Diwali night were found to be significantly higher than daytime concentrations for Pre Diwali (control). The inter correlation of metals between Ca with Pb, Zn with Ni and Cr, Cu with Co, Co with Mn, Ni with Cd, Mn with Cd, Ni with Cd and Cr, and Cr with Cd showed significant relation either at p < 0.05 or P < 0.01 levels, which indicated that their sources were the same. The metals Cu, Co, Ni, Cr and Cd showed significant (p < 0.01) association with PM(10). These results indicate that fireworks during Diwali festival affected the ambient air quality adversely due to emission and accumulation of PM(10), SO(2), NO( x ) and trace metals.

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“…A slight reduction of RBC and HGB levels were found in workers exposed to pure Co dust 4) . In subjects that living near to Mn mining district blood Pb and Mg were highly correlated; there was an inverse relation to HGB 5) . Erythropoietin controlled RBC production, whose synthesis in its turn is induced from the transcription of the Hypoxia Inducible Factor 1 (HIF-1).…”

Section: Discussionmentioning

confidence: 92%

“…noise) and psycho-social stressors. Studies in literature have suggested that urban pollutants as lead (Pb) 1,2) , sulphur dioxide (SO 2 ) 3) , cobalt (Co) 4) , manganese (Mn) 5) , nikel (Ni) 6) , carbon monoxide (CO) 7) , methanol (CH 3 OH) and methyl-ter-butyl-ether (MTBE) 8) may cause alterations of red blood cells (RBC), hemoglobin (HGB) and hematocrit (HCT) values. The class of workers investigated in this study was constituted by traffic police of a big Italian city, for whom we have already studied the environmental and biological levels of some urban pollutants in previous researches.…”

Section: Introductionmentioning

confidence: 99%

Hemopoietic System in Traffic Police Exposed to Urban Stressors

et al. 2008

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The aim of the study is to evaluate if occupational exposure to urban stressors could cause alterations in red blood cells (RBC), hemoglobin (HGB), hematocrit (HCT), mean cell volume (MCV), mean cell hemoglobin (MCH), mean corpuscular hemoglobin concentrations (MCHC) in traffic police compared to a control group. 694 subjects were included in the study: 347 traffic police and 347 controls matched by sex, age and length of service after excluding the subjects with the principal confounding factors. The levels of RBC, HGB, HCT were significantly higher in male (respectively p<0.001, p<0.05, p<0.01) and in female (respectively p<0.05, p<0.001, p<0.01) traffic police than in controls. The authors hypothesise that occupational exposure to urban stressors in traffic police can alter hemopoietic system.

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Exposure to Manganese: Health Effects on the General Population, a Pilot Study in Central Mexico

Cited by 121 publications

References 35 publications

The Challenge Posed to Children's Health by Mixtures of Toxic Waste: The Tar Creek Superfund Site as a Case-Study

The Challenge Posed to Children's Health by Mixtures of Toxic Waste: The Tar Creek Superfund Site as a Case-Study

Ambient air quality of Lucknow City (India) during use of fireworks on Diwali Festival

Hemopoietic System in Traffic Police Exposed to Urban Stressors

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