Exposure to mixed chemicals elevated triiodothyronine (T3) and follicle-stimulating hormone (FSH) levels: epidemiology and in silico toxicogenomic involvement

Nguyen, Hai Duc

doi:10.1007/s11356-023-28704-5

Cited by 1 publication

(1 citation statement)

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Using analysis of protein-protein interaction enrichment (PPIE) data, Hai Duc Nguyen demonstrated three major molecular mechanisms through which mercury affects the thyroid, namely the selenium micronutrient network, the IL-17 signaling pathway, and the oxidative stress response. It is also proven that poorly differentiated thyroid cancer and primary hyperthyroidism are the main mercuryinduced diseases of this organ [14].…”

Section: Ivb Mercury and Thyroid Pathologiesmentioning

confidence: 99%

Thyroid Response to Mercury: Varied Effects on Function and Structure - A Review of the Latest Research

Kubicka-Figiel,

Martyka,

Taborska

2024

J Educ Health Sport

View full text Add to dashboard Cite

Introduction In the current era of burgeoning industry, our exposure to various detrimental environmental factors, including mercury, has become increasingly prevalent. Recognized by the World Health Organization (WHO) as one of the most significant threats to public health, mercury induces a multitude of harmful effects on the entire body. Our focus in this article will be directed towards examining the specific impact of mercury on the thyroid. Purpose of the study The purpose of the study was to review the latest literature on the effects of mercury on the thyroid gland. Materials and Methodology Literature selections of medical databases PubMed and Google Scholar from the last six years (2017-2023) were performed. Articles were searched in English using the following key words: mercury, thyroid. Results Research consistently confirms mercury accumulation in thyroid cells, increasing with age. Mercury exposure influences thyroid function, raising the risk of hormonal issues and potential thyroid cancer. It also interacts with other elements, compounding adverse effects on the thyroid. Conclusion Presently, there is a limited number of studies specifically addressing the effects of mercury on the human thyroid gland. Consequently, it is probable that the full spectrum of its impacts on the thyroid has not yet been thoroughly investigated. Further research is imperative to delve into this subject comprehensively. Additionally, there is an urgent call for initiatives aimed at enhancing public awareness regarding the sources of mercury in the environment and food, along with strategies to mitigate exposure to this harmful substance.

show abstract

Section: Ivb Mercury and Thyroid Pathologiesmentioning

confidence: 99%