Exposure to per- and polyfluorinated alkyl substances in pregnant Brazilian women and its association with fetal growth

Souza, Marília Cristina Oliveira; Saraiva, Maria da Conceição Pereira; Honda, Masato; Barbieri, Marco Antônio; Bettiol, Heloísa; Barbosa, Fernando; Kannan, Kurunthachalam

doi:10.1016/j.envres.2020.109585

Cited by 38 publications

(14 citation statements)

References 41 publications

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“…Souza et al 2020 also found a significant association between socioeconomic status and PFOS/PFOA levels; more affluent women had higher concentrations of PFASs. Whole blood concentrations of PFOS and PFOA were also significantly associated with fetal growth restriction in pregnant Brazilian women [51].…”

Section: Prenatal Maternal Infantmentioning

confidence: 93%

“…There are few studies of PFAS contamination from Central and South America. However, a recent study assessing whole blood in Brazilian pregnant women found a significant positive association between PFOS and PFOA and fetal growth restriction [51]. A study from Denmark and Faroe Islands found evidence suggesting links between PFAS levels and increased odds of asthma in children at ages 5 and 13 [52].…”

Section: Various Countries Africa Central America South Americamentioning

confidence: 97%

“…PFOS and PFOA can cross the placental barrier between mother and child and alter the size, birth weight, Intrauterine Growth (IUGR), and gestational age [51]. Preterm birth, or Intrauterine Growth Restriction (IUGR), has been associated with increased risk for several diseases later in life, including cardiovascular disease, obesity, and endocrine disorders.…”

Section: Prenatal Maternal Infantmentioning

confidence: 99%

“…Preterm birth, or Intrauterine Growth Restriction (IUGR), has been associated with increased risk for several diseases later in life, including cardiovascular disease, obesity, and endocrine disorders. A study in Brazil examined the potential links between PFASs concentrations in the whole blood samples of 252 pregnant mothers and preeclampsia, low birth weight, preterm birth, and IUGR [51]. The study in Brazil found no significant association between increasing PFOS and PFOA and preterm birth, preeclampsia, and low birth weight.…”

Section: Prenatal Maternal Infantmentioning

confidence: 99%

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Per and polyfluoroalkyl substances scientific literature review: water exposure, impact on human health, and implications for regulatory reform

Chohan

Petaway

Rivera-Diaz

et al. 2020

Reviews on Environmental Health

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Among other emerging contaminants in water, per and polyfluoroalkyl substances (PFASs) have garnered international attention from the scientific community on a global scale. Some countries, such as the United States, have found that PFASs are present in humans on a wide scale. Although two PFASs have been widely studied-Perfluorooctanoic acid and Perfluorooctanesulfonic acid-many more PFASs are being created by industry and are either not known, not studied, or both. The objective of this literature review on PFASs is to give an overview of the information available about PFASs related to human exposure. The information from this literature review on the exposure of humans to PFASs through drinking water and the lack of many conventional drinking water treatment systems' ability to remove PFASs (particularly short-chain PFASs) suggests that current regulatory limits are insufficient to adequately protect humans. This is especially true for particularly vulnerable populations such as infants, young children, and developing children (pubescent). The gaps in the current knowledge and in current regulatory approaches could have long-term effects on human health.

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Section: Prenatal Maternal Infantmentioning

confidence: 93%

Section: Various Countries Africa Central America South Americamentioning

confidence: 97%

Section: Prenatal Maternal Infantmentioning

confidence: 99%

Section: Prenatal Maternal Infantmentioning

confidence: 99%

See 2 more Smart Citations

Per and polyfluoroalkyl substances scientific literature review: water exposure, impact on human health, and implications for regulatory reform

Chohan

Petaway

Rivera-Diaz

et al. 2020

Reviews on Environmental Health

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show abstract

“…To our knowledge, only one study has described PFOA and PFOS levels during pregnancy and their possible effects on birth outcomes in Brazil. 19 This study aimed to identify predictors of serum PFOA and PFOS concentrations in pregnant women residing in the city of Rio de Janeiro and estimate their associations with birth outcomes.…”

Section: Introductionmentioning

confidence: 99%

Serum levels of perfluorooctanoic acid and perfluorooctane sulfonic acid in pregnant women: Maternal predictors and associations with birth outcomes in the PIPA Project

Santos

Meyer

Dabkiewicz

et al. 2021

J of Obstet and Gynaecol

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Aim: Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) are persistent pollutants associated with adverse birth outcomes. This study aimed to identify predictors of blood PFOA and PFOS concentrations in pregnant women and to estimate their associations with birth outcomes in Brazil. Methods: We conducted a cross-sectional study with 139 pregnant women enrolled in the pilot study of the Rio Birth Cohort Study on Environmental Exposure and Childhood Development (PIPA Project). Multiple linear regression was used to estimate associations between PFOA and PFOS with maternal predictors and birth outcomes. Results: Higher levels of PFOA were observed in women aged 16-19 and 20-39 years, while fish consumption from 0.6 to 2.0 times per week was associated with lower levels of the substance. PFOS levels were higher in women living in houses with up to four rooms but lower in those who reported passive exposure to smoking. Increased newborn length and head circumference were also associated with higher maternal levels of PFOA. Conclusions: In our study, age, fish consumption, passive smoking, and the number of rooms in the house were predictors of maternal PFAS levels. However, we did not observe significant associations between maternal plasma PFAS concentrations and birth outcomes.

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Per‐ and Polyfluoroalkyl Substances (PFAS) in Drinking Water

Kougias,

Killius,

Collins

et al. 2024

Human and Ecological Risk Assessment

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Exposure to per- and polyfluorinated alkyl substances in pregnant Brazilian women and its association with fetal growth

Cited by 38 publications

References 41 publications

Per and polyfluoroalkyl substances scientific literature review: water exposure, impact on human health, and implications for regulatory reform

Per and polyfluoroalkyl substances scientific literature review: water exposure, impact on human health, and implications for regulatory reform

Serum levels of perfluorooctanoic acid and perfluorooctane sulfonic acid in pregnant women: Maternal predictors and associations with birth outcomes in the PIPA Project

Per‐ and Polyfluoroalkyl Substances (PFAS) in Drinking Water

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