Exposure to perchlorate, nitrate and thiocyanate was associated with the prevalence of cardiovascular diseases

Wang, Long; Fu, Zhi; Zheng, Jie; Wang, Shuai; Yan, Peng; Gao, Beibei; Mo, Xuming; Liang, Ping; Huang, Jinyu

doi:10.1016/j.ecoenv.2022.113161

Cited by 16 publications

(4 citation statements)

References 25 publications

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“…Questions were used for determine each type of CVD. Participants was defined if they answered “Yes” to the questionnaire “Have you ever been told by a doctor that you had heart failure, heart attack, coronary heart disease, stroke and congestive heart failure?” [ 29 ]. CKD was defined as urinary albumin to creatinine ratio > 30 mg/g or estimated glomerular filtration rate < 60 mL/min/1.73m 2 according to the “KDIGO 2021 Guidelines” [ 30 ].…”

Section: Methodsmentioning

confidence: 99%

Association between dietary patterns and the risk of all-cause mortality among old adults with obstructive sleep apnea

Zhao,

Gao,

et al. 2024

BMC Geriatr

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Background Obstructive sleep apnea (OSA) was associated with the increased cardiovascular events and all-cause mortality. And anti-inflammatory dietary has potential to improve the prognosis of OSA. This study aimed to investigate the association of anti-inflammatory dietary patterns with all-cause mortality among individuals with OSA. Methods This retrospective cohort study involved 1522 older adults with OSA from 2005 to 2008 in the National Health and Nutrition Examinations Survey (NHANES). Mortality status was determined by routine follow-up through December 31, 2019, using the National Death Index. Anti-inflammatory dietary patterns included Alternate Mediterranean Diet Score (aMED), Healthy Eating Index-2015 (HEI-2015), and Alternate Healthy Eating Index-2010 (AHEI-2010). Weighted Cox proportional hazard regression models were performed to investigate the association between anti-inflammatory dietary pattern and all-cause mortality. Results After a median follow-up of 131 months, 604 participants were recorded all-cause mortality. The mean age of OSA patients was 68.99 years old, of whom 859 were male (52.34%). Higher adherence of aMED (HR = 0.61, 95%CI: 0.48 to 0.78) and HEI-2015 (HR = 0.75, 95%CI: 0.60 to 0.95) were associated with lower all-cause mortality risk in the elderly with OSA. Conversely, no association was found between AHEI-2010 dietary pattern and all-cause mortality in individuals with OSA. In the component analysis of aMED, it was found that a higher intake of vegetables and olive oil potentially contributes to the reduction all-cause mortality risk in the elderly with OSA (HR = 0.60, 95%CI: 0.48 to 0.76; HR = 0.67, 95%CI: 0.63 to 0.71). Conclusion Higher adherence to the aMED and the HEI-2015 was associated with a lower risk of all-cause mortality in OSA. Future interventions in the elderly with OSA should considering adopting anti-inflammatory dietary patterns.

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Section: Methodsmentioning

confidence: 99%

Association between dietary patterns and the risk of all-cause mortality among old adults with obstructive sleep apnea

Zhao,

Gao,

et al. 2024

BMC Geriatr

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“…The NHANES data have been used in many public health and epidemiology studies. [26][27][28][29][30][31][32] Demographic, physical examination, prescription drug (RXD) and dietary supplement (DS) use 8 , and health insurance information were extracted from NHANES for survey years 2003 -2014 (6 survey cycles). This is the same cycle used in a previous study 33 regarding DS use which allowed for comparison.…”

Section: Methodsmentioning

confidence: 99%

Assessing the Use of Prescription Drugs in Obese Respondents in the National Health and Nutrition Examination Survey

Barrett

Xing

Steidley

et al. 2021

Preprint

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IntroductionObesity is a common disease and a known risk factor for many other conditions such as hypertension, type 2 diabetes, and cancer. Treatment options for obesity include lifestyle changes, pharmacotherapy, and surgical interventions such as bariatric surgery. In this study, we examine the use of prescription drugs and dietary supplements by the individuals with obesity.MethodsWe conducted a cross-sectional analysis of the National Health and Nutrition Examination Survey (NHANES) data 2003-2014. We used multivariate logistic regression to analyze the correlations of demographics and obesity status with the use of prescription drugs and dietary supplement use. We also built machine learning models to predict prescription drug and dietary supplement use using demographic data and obesity status.ResultsIndividuals with obesity are more likely to take cardiovascular agents (OR=1.265, 95% CI 1.222-1.311) and metabolic agents (OR=1.398, 95% CI 1.343-1.456) than individuals without obesity. The best performing prediction model for predicting prescription drugs had the accuracy of 74.5% and the AUROC of 0.817.ConclusionsThis study can inform clinical practice and patient education of the use of prescription drugs and dietary supplements and their correlation with obesity.

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“…However, the beneficial roles of PNT have also been reported. For example, some studies have demonstrated that dietary nitrate might have a cardiovascular protective effect [16,17] . However, to date, no epidemiological studies have illustrated clear associations between PNT exposure and renal function in the general population.…”

Section: Introductionmentioning

confidence: 99%

Environmental exposure to perchlorate, nitrate, and thiocyanate in relation to chronic kidney disease in the general US population, NHANES 2005–2016

et al. 2023

Chinese Medical Journal

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Background: Few studies have explored the impact of perchlorate, nitrate, and thiocyanate (PNT) on kidney function. This study aimed to evaluate the association of urinary levels of PNT with renal function as well as the prevalence of chronic kidney disease (CKD) among the general population in the United States. Methods: This analysis included data from 13,373 adults (≥20 years) from the National Health and Nutrition Examination Survey 2005 to 2016. We used multivariable linear and logistic regression, to explore the associations of urinary PNT with kidney function. Restricted cubic splines were used to assess the potentially non-linear relationships between PNT exposure and outcomes. Results: After traditional creatinine adjustment, perchlorate (P-traditional) was positively associated with estimated glomerular filtration rate (eGFR) (adjusted β: 2.75; 95% confidence interval [CI]: 2.25 to 3.26; P < 0.001), and negatively associated with urinary albumin-to-creatinine ratio (ACR) (adjusted β: −0.05; 95% CI: −0.07 to −0.02; P = 0.001) in adjusted models. After both traditional and covariate-adjusted creatinine adjustment, urinary nitrate and thiocyanate were positively associated with eGFR (all P values <0.05), and negatively associated with ACR (all P values <0.05); higher nitrate or thiocyanate was associated with a lower risk of CKD (all P values <0.001). Moreover, there were L-shaped non-linear associations between nitrate, thiocyanate, and outcomes. In the adjusted models, for quartiles of PNT, statistically significant dose–response associations were observed in most relationships. Most results were consistent in the stratified and sensitivity analyses. Conclusions: Exposures to PNT might be associated with kidney function, indicating a potential beneficial effect of environmental PNT exposure (especially nitrate and thiocyanate) on the human kidney.

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Exposure to perchlorate, nitrate and thiocyanate was associated with the prevalence of cardiovascular diseases

Cited by 16 publications

References 25 publications

Association between dietary patterns and the risk of all-cause mortality among old adults with obstructive sleep apnea

Association between dietary patterns and the risk of all-cause mortality among old adults with obstructive sleep apnea

Assessing the Use of Prescription Drugs in Obese Respondents in the National Health and Nutrition Examination Survey

Environmental exposure to perchlorate, nitrate, and thiocyanate in relation to chronic kidney disease in the general US population, NHANES 2005–2016

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