Exposure to pyrogallol impacts the hemato-biochemical endpoints in catfish (Clarias gariepinus)

Hamed, Mohamed; Martyniuk, Christopher J.; Said, Rashad E.M.; Soliman, Hatem; Badrey, Ahmed E. A.; Hassan, Elhagag Ahmed; Abdelhamid, Hani Nasser; Osman, Alaa G. M.; Sayed, Alaa El‐Din H.

doi:10.1016/j.envpol.2023.122074

Cited by 18 publications

(5 citation statements)

References 92 publications

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“…Hereditary elliptocytosis, associated with mutations in genes encoding erythro‐membrane proteins such as α ‐spectrin, ß‐spectrin, and glycophorin C/Gerbich blood groups, causes defects in the horizontal cytoskeletal network [54]. Acquired elliptocytosis in fish, documented more frequently than hereditary cases, results in the formation of classical elliptocytes with parallel sides and a long axis more than twice the length of the short axis, as well as pencil cells characterized by a long axis more than three times the length of the short axis, commonly observed in severe anemic conditions [59, 64]. The elliptical shape emerges gradually due to mechanical stress in the circulation, caused by defects in erythro‐membrane proteins, leading to increased mechanical weakness and membrane fragility [167].…”

Section: Types Of Poikilocytosis In Fishmentioning

confidence: 99%

“…Mutations in slc4a destabilize the erythro‐membrane, leading to hereditary spherocytosis [10]. Additionally, disruptions in proteins like β ‐spectrin and ankyrin, which are essential for maintaining erythro‐membrane stability and deformability, have been linked to hereditary poikilocytosis in fish [44, 54, 64, 173]. These genetic defects in key proteins contribute to the loss of erythrocyte elasticity and deformability, representing fundamental causes of hereditary poikilocytosis in aquaculture, consequently impacting crucial physiological aspects in fish.…”

Section: Types Of Poikilocytosis In Fishmentioning

confidence: 99%

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Visualization of poikilocytosis as an emerging erythrocytic biomarker for fish health assessment

Bardhan,

Abraham,

Das

et al. 2024

Animal Research and One Health

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Fish health assessment is essential for maintaining sustainable aquatic ecosystems and ensuring the well‐being of wild and farmed fish populations. Hematological parameters are crucial indicators of fish health, with poikilocytosis emerging as a fundamental marker with significant diagnostic value. Poikilocytosis refers to abnormally shaped erythrocytes in bloodstream, reflecting underlying physiological and pathological conditions. Poikilocytosis can occur in various fish species and can be influenced by environmental stressors, infectious agents, nutritional deficiencies, and exposure to pollutants. Morphological alterations in erythrocytes, such as acanthocytes, echinocytes, dacrocytes, schistocytes, spherocytes, and codocytes are common poikilocytes in fish. Understanding the relationship between poikilocytosis and fish health has important implications for disease diagnosis, monitoring, surveillance, and management. By quantifying poikilocytic changes, researchers and veterinarians can differentiate normal variations from pathological conditions, facilitating targeted interventions and treatment strategies. While most studies have focused on heavy metal toxicity, stressors, nutritional deficiencies, pollutants, and therapeutics, the etiological induction of poikilocytosis in fish health has been overlooked. Nonetheless, poikilocytosis remains a valuable biomarker for assessing fish health and their environment. This review highlights piscine poikilocytosis as a significant fish hematological biomarker and its importance in understanding their health and culture conditions.

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Section: Types Of Poikilocytosis In Fishmentioning

confidence: 99%

Section: Types Of Poikilocytosis In Fishmentioning

confidence: 99%

Visualization of poikilocytosis as an emerging erythrocytic biomarker for fish health assessment

Bardhan,

Abraham,

Das

et al. 2024

Animal Research and One Health

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“…The African catfish ( C. gariepinus ), a widely distributed freshwater fish, can be found in both natural and developed aquatic habitats, according to Mohamed et al (2022) and Hamed et al (2023) . Additionally, because of its well-documented biology, widespread usage in aquaculture, use as a component of human food, and a good fish model for toxicological, immunological, and histopathological studies ( Mekkawy et al, 2010 ; Osman et al, 2019 ; Mukherjee et al, 2022 ), it has been employed as a valuable research tool.…”

Section: Introductionmentioning

confidence: 99%

Deleterious effects of polypropylene released from paper cups on blood profile and liver tissue of Clarias gariepinus: bioremediation using Spirulina

Eid,

Mahmoud,

Sayed

2024

Front. Physiol.

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Despite numerous studies on microplastics, the biological impacts of polypropylene microplastics (PP-MPs) and its toxicity on freshwater fish have yet to be fully revealed. The purpose of this research was to look at the potentially harmful effects of PP-MPs in freshwater African catfish Clarias gariepinus and bioremediation using Spirulina. After acclimatization to laboratory conditions, 108 fish (125 ± 3 gm and 27 ± 2 cm) were assigned into triplicate six experimental groups (12 fish/group), a control group, Spirulina group (SP), PP-MP-treated groups (0.14 and 0.28 mg/l PP-MPs), and PP-MP + Spirulina-treated groups (0.14 mg/l PP-MPs + 200 mg/L SP and 0.28 mg/l PP-MPs +200 mg/L SP) for 15-day exposure and 45-day recovery after that. The hematological parameters exhibiting significance (RBCs, Hct, Hb, and MCV) or non-significance (MCH and MCHC) either decreased with the increase in PP-MP doses from 0.0 in the control to 0.28 mg/L red blood cells (RBCs), hematocrit (Hct), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), hemoglobin (Hb) and platelets or increased with such an increase in doses (mean corpuscular volume (MCV)). The liver enzyme activity, aspartate aminotransferase (AST), alkaline phosphatase (ALP), and alanine aminotransferase (ALT) exhibited non-significant (p ≥ 0.05) or significant (p < 0.05) increases in (0.14 and 0.28 mg/L) PP-MP-exposed groups, respectively, except ALP. Furthermore, there was a significant (p < 0.05) or non-significant (p ≥ 0.05) increase in 0.14 and 0.28 mg/l PP-MP +200 mg/L-exposure groups, respectively, compared to the control group and the same exposure group without Spirulina. In comparison to the control group, PP-MPs (0.14 and 0.28 mg/L) induced a significant (p < 0.05) increase in the percentage of poikilocytosis and nuclear abnormalities of RBCs. The liver tissue from fish exposed to PP-MPs exhibited varying degrees of pathological changes. These results indicated that these pathological changes increased with PP-MP concentration, suggesting that the effect of PP-MPs was dose-dependent. After 45 days of recovery under normal conditions, it was obvious that there was a significant improvement in the percentage of poikilocytosis and nuclear abnormalities of RBCs, as well as a non-significant improvement in hemato-biochemical parameters and liver tissue.

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“…Due to the widespread use of PG, it is consequentially discharged into industrial effluents and, thus, adds hazards into aquatic environments. PG can cause oxidative stress, which may lead to biological poisoning or even death [3][4][5]. The abundance of PG in rivers is about 4 µM [6].…”

Section: Introductionmentioning

confidence: 99%

Pyrogallol Detection Based on the Cobalt Metal–Organic Framework of Nanomaterial-Enhanced Chemiluminescence

Wang

Liu

et al. 2023

Chemosensors

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The cobalt metal–organic framework (Co-MOF) is a kind of crystalline porous material within a periodic network structure, which is formed via the self-assembly of a Co metal center and a bridged organic ligand. In this paper, a Co-MOF was facilely synthesized via an ultrasonic method and applied to enhance the chemiluminescence (CL) emission of the NaIO4-H2O2 system. The synthesized Co-MOF was nanosheet-like in nature and stacked in 2–3-micrometer flower shapes. Compared to the NaIO4-H2O2 system without a Co-MOF, the CL intensity of the Co-MOF-NaIO4-H2O2 system was enhanced about 70 times. This CL mechanism was determined to be a result of the synergistic effects of chemiluminescence resonance energy transfer (CRET) and electron–hole annihilation (EHA). The Co-MOF not only acted as a catalyst to accelerate the generation of reactive oxygen species in the CL reaction, but also worked as an emitter to further enhance the CL. Based on the Co-MOF-NaIO4-H2O2 system, a highly sensitive CL analysis method was established for pyrogallol (PG) detection. Addition of PG into the CL system generated 1O2*, which could transfer energy to the Co-MOF and further enhance the CL response. The enhanced CL was linear with the PG concentration. The CL analysis method exhibited a linear range of 1 × 10−4 M to 1 × 10−7 M, as well as having a linear correlation coefficient of 0.9995 and a limit of detection of (S/N = 3) of 34 nM.

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Exposure to pyrogallol impacts the hemato-biochemical endpoints in catfish (Clarias gariepinus)

Cited by 18 publications

References 92 publications

Visualization of poikilocytosis as an emerging erythrocytic biomarker for fish health assessment

Visualization of poikilocytosis as an emerging erythrocytic biomarker for fish health assessment

Deleterious effects of polypropylene released from paper cups on blood profile and liver tissue of Clarias gariepinus: bioremediation using Spirulina

Pyrogallol Detection Based on the Cobalt Metal–Organic Framework of Nanomaterial-Enhanced Chemiluminescence

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