Extreme temperatures, drought, and high soil salinity are some of the significant abiotic stresses that can severely impact crop yields, posing a threat to global food production. Comprehensive studies on model plant species are crucial for understanding their biochemical, physiological, and molecular responses to abiotic stresses. Identifying stress response mechanisms and potential targets can aid in developing stress-tolerant crop varieties. Additionally, elucidating the functions of reactive oxygen species is essential for this research area. In model plants, the perception of abiotic stresses is a complex phenomenon that entails intricate interactions between hormones, gene regulation, and physiology. The presence of specific stress receptors and sensors contributes to this perception. Activating signaling pathways involves a cascade of events, starting with generating reactive oxygen species, then calcium signaling and MAP kinase signaling. Because of these processes, transcription factors and genes susceptible to stress are ultimately activated in the latter stages. It starts with a series of physiological and biochemical modifications, which entail adjustments in photosynthesis and the accumulation of osmoprotectants. We have gained significant insights from studying model plant stress responses, but there remain considerable challenges in effectively applying these findings to enhance crop resilience. These challenges contribute to reproducing the results across various species. These difficulties arise because of phenotypes, molecular mechanisms, and genetic differences. The utilization of model plants will persist in their crucial role as essential systems for unraveling the complexities of plant stress responses. They will play a vital role in overcoming present constraints, particularly in areas such as the mathematical modeling of plant physiology. The exploration of gene function across species can significantly contribute to efforts aimed at improving crops. The key to addressing threats to global food security and promoting crop stress resilience lies in adopting a multi-pronged approach that uses model plant systems.