Expression and Clinical Trends of Pct Combined with Lactate Clearance in Sepsis

Abstract

Objective. To study the expression and clinical trend of procalcitonin (Pct) + lactate clearance in sepsis. Methods. A total of 63 septic shock patients enrolled in our hospital from March 2018 to March 2021 were recruited as group A, and the 87 septic patients admitted during the same period were recruited as group B. The Pct, lactic acid, and lactate clearance were compared between the two groups. Results. The Pct and lactic acid in group A were higher than those in group B at the time of diagnosis, 1 d, 2 d, and 3 d after treatment, but the lactate clearance rate at 1 d, 2 d, and 3 d after treatment was lower than that in group B ( P < 0.05 ). The Pct and lactate at the time of diagnosis, 1 d, 2 d, and 3 d after treatment in the good prognosis group were lower than those in the poor prognosis group, but the lactate clearance rate at 1 d, 2 d, and 3 d after treatment was higher than that in the poor prognosis group ( P < 0.05 ). Disease severity and prognosis were positively correlated with Pct and lactate, but negatively correlated with lactate clearance rate ( P < 0.05 ). Conclusions. Pct and lactate clearance rate might serve as accurate predictors of the severity of sepsis and prognosis. It merits promotion in clinical setting.

The Value of Serum Procalcitonin, Thromboelastography Combined with Platelet Count in Predicting the Short-Term Progression of Septic Shock in the Intensive Care Unit

“…In recent years, more and more research has shown that 4 , 5 specific and sensitive infection-related markers such as procalcitonin (PCT) not only have important reference value for the early diagnosis, evaluation of infection severity and prognosis of sepsis, but also can easily guide the use of antibiotics. High concentration of PCT may develop into severe bacterial sepsis or septic shock.…”

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“…If the perfusion of tissue is poor and the oxygen supply is inadequate, metabolism will be affected. In those with sepsis, disease severity is directly coinciding with tissue perfusion level and oxygen supply [10]. Other promising biomarkers are Presepsin (P-SEP) and Mid-regional proadrenomedullin (MR-ProADM).…”

Retracted: Expression and Clinical Trends of Pct Combined with Lactate Clearance in Sepsis

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [ 1 ]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process: Discrepancies in scope Discrepancies in the description of the research reported Discrepancies between the availability of data and the research described Inappropriate citations Incoherent, meaningless and/or irrelevant content included in the article Peer-review manipulation …”

“…Tis article has been retracted by Hindawi following an investigation undertaken by the publisher [1]. Tis investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process:…”