2023
DOI: 10.3390/ijms241512277
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Expression and Regulatory Mechanisms of MicroRNA in Cholesteatoma: A Systematic Review

Karolina Dżaman,
Katarzyna Czerwaty,
Torsten E. Reichert
et al.

Abstract: Cholesteatoma is a temporal bone disease characterized by dysfunctions of keratinocytes. MicroRNAs (miRNAs) are evolutionary conserved noncoding RNAs that regulate mRNA expression. They can be packaged into exosomes and transported to target cells that can be used in the future therapy of cholesteatoma. This study aimed to collect knowledge on the role of miRNAs and exosomal miRNAs in cholesteatoma and was conducted according to the PRISMA guidelines for systematic reviews. Four databases were screened: Pubmed… Show more

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