Expression and scale-up production of recombinant human papillomavirus type 52 L1 protein in methylotrophic yeast Hansenula polymorpha

Chairunnisa, Sheila; Mustopa, Apon Zaenal; Bela, Budiman; Firdaus, Moh Egy Rahman; Irawan, Shasmita; Arifah, Rosyida Khusniatul; Irawan, Herman; Nurfatwa, Maritsa; Umami, Rifqiyah Nur; Ekawati, Nurlaili; Hertati, Ai; Hasan, Nurhasni

doi:10.1016/j.jgeb.2023.100342

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Book1

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Molecular dynamics simulation and purification of chimeric L1/L2 protein from human papillomavirus type 52 expressed in Escherichia coli BL21 (DE3)

Al Adawiah,

Zaenal Mustopa,

Budiarti

et al. 2024

Journal of Immunoassay and Immunochemistry

View full text Add to dashboard Cite

Molecular dynamics simulation and purification of chimeric L1/L2 protein from human papillomavirus type 52 expressed in Escherichia coli BL21 (DE3)

Al Adawiah,

Zaenal Mustopa,

Budiarti

et al. 2024

Journal of Immunoassay and Immunochemistry

View full text Add to dashboard Cite

Advancements in Human Vaccine Development: From Traditional to Modern Approaches

Aribi

2024

Pharmaceutical Science

View full text Add to dashboard Cite

Vaccinology, the scientific discipline focused on vaccines, has evolved from combating infectious diseases to addressing a wide array of a broad spectrum of health concerns, including autoimmune disorders, neurodegenerative diseases, and allergies, with promising therapeutic vaccines for cancer utilizing tumor-infiltrating lymphocytes (TILs) and adoptive cell therapy, like chimeric antigen receptor T-cell (CAR-T-cells), CAR-natural killer cells (CAR-NK cells), and CAR-macrophages (CAR-M), as well as necrotic and necroptotic cancer cells. Additionally, ongoing research endeavors aim to develop anti-addiction vaccines. This chapter offers a comprehensive exploration of vaccinology, encompassing fundamental immunity concepts, the role of adjuvants, and various vaccine types. It traces the evolution of vaccine development from traditional methods to modern innovations like messenger ribonucleic acid (mRNA) vaccines, exemplified by those developed for coronavirus disease 2019 (COVID-19), which offer rapid adaptability to emerging variants. The significance of measuring neutralizing antibodies in assessing vaccine efficacy and effectiveness, which is crucial for guiding epidemic responses, is underscored. By delving into historical and contemporary developments, addressing current challenges, and envisioning future directions, this chapter fosters a deeper understanding of vaccinology and encourages critical reflection on innovative solutions to global health challenges.

show abstract

Expression and scale-up production of recombinant human papillomavirus type 52 L1 protein in methylotrophic yeast Hansenula polymorpha

Cited by 2 publications

References 27 publications

Molecular dynamics simulation and purification of chimeric L1/L2 protein from human papillomavirus type 52 expressed in Escherichia coli BL21 (DE3)

Molecular dynamics simulation and purification of chimeric L1/L2 protein from human papillomavirus type 52 expressed in Escherichia coli BL21 (DE3)

Advancements in Human Vaccine Development: From Traditional to Modern Approaches

Contact Info

Product

Resources

About