2021
DOI: 10.30651/jqm.v5i2.6354
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Expression of Brain-Derived Neurotrophic Factor in the Brain of Depressed Mice: Systematic Literature Review

Abstract: Introduction: Chronic stress exposure plays a role as a risk factor for depression. In chronic stress, there is prunning of nerve cell dendrites so that depression becomes irreversible. Depression is caused by low serotonin (5-HT2) neurotransmitters in the postsynaptic cleft. Recent findings in experimental animals indicate that serotonergic preparations are required to increase serotonin levels in the synapse opening, thereby triggering the formation of new dendrites to make depression reversible. The differe… Show more

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