1999
DOI: 10.1016/s0006-8993(98)00828-2
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Expression of Fos immunoreactivity in rat brain during dehydration: effect of duration and timing of water deprivation

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Cited by 37 publications
(34 citation statements)
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“…Our finding that Fos was increased in magnocellular and parvocellular PVN neurons in water-restricted animals is consistent with previous studies showing that water deprivation-induced dehydration increases Fos expression in PVN and SON neurons compared with hydrated controls (15,20,29,40,43,48). However, these studies did not assess the phenotype of PVN neurons expressing Fos.…”
Section: Discussionsupporting
confidence: 92%
“…Our finding that Fos was increased in magnocellular and parvocellular PVN neurons in water-restricted animals is consistent with previous studies showing that water deprivation-induced dehydration increases Fos expression in PVN and SON neurons compared with hydrated controls (15,20,29,40,43,48). However, these studies did not assess the phenotype of PVN neurons expressing Fos.…”
Section: Discussionsupporting
confidence: 92%
“…In support of this, we found that the magnitude of the depressor response to Kyn is correlated with the basal level of osmolality. Furthermore, a previous study investigating brain regions activated during water deprivation, as assessed by expression of the inducible transcription factor c-Fos, indicates that activation of some sites, such as the subfornical organ, is greater after 48 h than after 24 h of water deprivation (22).…”
Section: Discussionmentioning
confidence: 94%
“…These magnocellular neurons in the SON and PVN project their axons to and along the base of the third ventricle, in the internal zone of the median eminence, to the posterior pituitary, at which site the neurosecretion of vasopressin and oxytocin occurs (16). Neurons at all levels of this pathway express c-fos in response to water deprivation (17)(18)(19).…”
Section: ␤-Gal Expression Extends Along Neuronal Processes Over Time mentioning
confidence: 99%