2023
DOI: 10.1016/j.wneu.2022.12.009
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Expression of Histone H1 in Rats with Traumatic Brain Injury and the Effect of the NLRP3 Inflammasome Pathway

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Cited by 4 publications
(4 citation statements)
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“…Shen et al reported that CY-09 inhibited the NLRP3 driven neuroinflammation in a PTZ-induced kindling mouse model, a chronic model of generalized seizures [144]. CY-09 repressed the expression of NLRP3, IL-1 and IL-18 in injured brain tissue in the rat TBI models [145]. The findings from Wang et al showed that CY-09 attenuates depression-like behaviors by inhibiting the NLRP3-mediated neuroinflammation in LPS-induced mice [146].…”
Section: Cy-09 (4-[[4-oxo-2-thioxo-3-[[3-(trifluoromethyl) Phenyl] Me...mentioning
confidence: 99%
“…Shen et al reported that CY-09 inhibited the NLRP3 driven neuroinflammation in a PTZ-induced kindling mouse model, a chronic model of generalized seizures [144]. CY-09 repressed the expression of NLRP3, IL-1 and IL-18 in injured brain tissue in the rat TBI models [145]. The findings from Wang et al showed that CY-09 attenuates depression-like behaviors by inhibiting the NLRP3-mediated neuroinflammation in LPS-induced mice [146].…”
Section: Cy-09 (4-[[4-oxo-2-thioxo-3-[[3-(trifluoromethyl) Phenyl] Me...mentioning
confidence: 99%
“…Shen et al reported that CY-09 inhibited the NLRP3 driven neuroinflammation in PTZ induced kindling mouse model, a chronic model of generalized seizures [146]. CY-09 repressed the expression of NLRP3, IL-1b and IL-18 in injured brain tissue in the rat TBI models [147]. The findings from Wang et al showed that CY-09 attenuates depression-like behaviors by inhibiting the NLRP3-mediated neuroinflammation in LPS-induced mice [148].…”
Section: Nlrp3 Inhibitors In Preclinical and Clinical Trial Phasementioning
confidence: 99%
“…Shen et al reported that CY-09 inhibited the NLRP3 driven neuroinflammation in a PTZ-induced kindling mouse model, a chronic model of generalized seizures [ 144 ]. CY-09 repressed the expression of NLRP3, IL-1β, and IL-18 in injured brain tissue in the rat TBI models [ 145 ]. The findings from Wang et al showed that CY-09 attenuates depression-like behaviors by inhibiting the NLRP3-mediated neuroinflammation in LPS-induced mice [ 146 ].…”
Section: Nlrp3 Inflammasome In Epilepsymentioning
confidence: 99%