Expression of Retinaldehyde Dehydrogenases in the Pituitary Glands of Fetus and Adult Mice
Yanan Wei,
Si Cheng,
Takehiro Tsukada
et al.
Abstract:Retinoic acid (RA) plays a critical role in cell growth and tissue development. RA is synthesized from retinoids through oxidation processes by the retinaldehyde dehydrogenase (Raldh) family. However, the expression of
Raldhs
during pituitary development and the identification of
Raldh
-expressing cells in the adult pituitary have not been fully elucidated. Here, we performed
in situ
hybridization to localize the three Raldh isoforms (
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