2013
DOI: 10.1186/2050-490x-1-8
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Expression of tropomyosin in relation to myofibrillogenesis in axolotl hearts

Abstract: The anatomy, function and embryonic development of the heart have been of interest to clinicians and researchers alike for centuries. A beating heart is one of the key criteria in defining life or death in humans. An understanding of the multitude of genetic and functional elements that interplay to form such a complex organ is slowly evolving with new genetic, molecular and experimental techniques. Despite the need for ever more complex molecular techniques some of our biggest leaps in knowledge come from nat… Show more

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Cited by 4 publications
(2 citation statements)
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“…On the Mexican axolotl model, suppression of the κTpm expression in the developing heart impaired myofibrillogenesis in cardiomyocytes and heart development [4,10]. Note that the presence of a minor amount of κTpm in the adult axolotl myocardium was also found [4,10].…”
Section: Introductionmentioning
confidence: 92%
See 1 more Smart Citation
“…On the Mexican axolotl model, suppression of the κTpm expression in the developing heart impaired myofibrillogenesis in cardiomyocytes and heart development [4,10]. Note that the presence of a minor amount of κTpm in the adult axolotl myocardium was also found [4,10].…”
Section: Introductionmentioning
confidence: 92%
“…The presence of κTpm led to a decrease in the calcium sensitivity tension relationship of skinned myocardial preparations but did not affect the maximum tension [7,9]. On the Mexican axolotl model, suppression of the κTpm expression in the developing heart impaired myofibrillogenesis in cardiomyocytes and heart development [4,10]. Note that the presence of a minor amount of κTpm in the adult axolotl myocardium was also found [4,10].…”
Section: Introductionmentioning
confidence: 98%