“…In other studies, human anterior uveal melanomas expressed high levels of VEGF as assessed by immunohistochemistry 21,52,53 . Elevated expression levels of VEGF, VEGFR1, and VEGFR2 have been documented in human eyes with intraocular tumors including retinoblastoma, iris and ciliary body adenomas, and choroidal melanomas 21,54,55 . Members of the VEGF family of proteins have been identified in a variety of canine nonocular neoplastic diseases including lymphoma, 56 cutaneous squamous cell carcinoma, 57 mammary carcinoma, 58 hemangiosarcoma, 30 and mastocytoma 59 .…”