2015
DOI: 10.5603/fhc.a2014.0032
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Expression of vascular endothelial growth factor and transforming growth factor alpha in rat testis during chronic renal failure

Abstract: Introduction. Vascular endothelial growth factor (VEGF) is known to influence testis function. Transforming growth factor alpha (TGF-a) is expressed in the postnatal testis, and has been demonstrated to stimulate testis development. Systemic diseases such as chronic renal failure (CRF) interfere with hypothalamic-pituitary-gonadal axis, which may cause defective steroidogenesis and gonadal functions. The aim of this study was to investigate the expression and localization of VEGF and TGF-a in testicular tissue… Show more

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