Expression profile of insulin-like growth factor system genes in muscle tissues during the postnatal development growth stage in ducks

Song, Chenling; Liu, H.-H.; Kou, Jiantao; Lv, Lishuang; Li, L.; Wang, W.-X.; Wang, J.-W.

doi:10.4238/2013.may.6.3

Cited by 6 publications

(4 citation statements)

References 46 publications

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“…The focus of this study is on the Igf2 gene and locus in nonmammalian vertebrates, where available information is far less extensive than in mammals (37)(38)(39)(40). Results based on the combinatorial analysis of public genomic and gene expression databases reveal remarkable conservation of overall locus organization and similarity of Igf2 exons and IGF2 proteins in Ͼ500 Myr of evolutionary diversification, and they support the idea that the Igf2 gene and its locus are phylogenetically ancient in vertebrates.…”

supporting

confidence: 52%

“…1E and 10A). Among the other species studied here, mature IGF2 was identical to the chicken protein in turkey, duck, and flycatcher; a single amino acid substitution was seen in zebra finch (Ile 39 to Phe), four changes were found in turtle (Arg 30 to Ser, Ile 39 to Phe, Lys 63 to Arg, and Ser 64 to Thr), and multiple differences were detected in the other species, including human ( Fig. 10A and Table 5).…”

Section: Igf2 Protein Sequences In Nonmammalian Vertebratesmentioning

confidence: 76%

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The insulin-like growth factor 2 gene and locus in nonmammalian vertebrates: Organizational simplicity with duplication but limited divergence in fish

Rotwein

2018

Journal of Biological Chemistry

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The small, secreted peptide, insulin-like growth factor 2 (IGF2), is essential for fetal and prenatal growth in humans and other mammals. Human and mouse genes are located within a conserved linkage group and are regulated by parental imprinting, with / being expressed from the paternally derived chromosome, and from the maternal chromosome. Here, data retrieved from genomic and gene expression repositories were used to examine the gene and locus in 8 terrestrial vertebrates, 11 ray-finned fish, and 1 lobe-finned fish representing >500 million years of evolutionary diversification. The analysis revealed that vertebrate genes are simpler than their mammalian counterparts, having fewer exons and lacking multiple gene promoters. genes are conserved among these species, especially in protein-coding regions, and IGF2 proteins also are conserved, although less so in fish than in terrestrial vertebrates. The locus in terrestrial vertebrates shares additional genes with its mammalian counterparts, including tyrosine hydroxylase (), insulin (), mitochondrial ribosomal protein L23 (), and troponin T3, fast skeletal type (), and both and are present in the locus in fish. Taken together, these observations support the idea that a recognizable was present in the earliest vertebrate ancestors, but that other features developed and diversified in the gene and locus with speciation, especially in mammals. This study also highlights the need for correcting inaccuracies in genome databases to maximize our ability to accurately assess contributions of individual genes and multigene families toward evolution, physiology, and disease.

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supporting

confidence: 52%

Section: Igf2 Protein Sequences In Nonmammalian Vertebratesmentioning

confidence: 76%

The insulin-like growth factor 2 gene and locus in nonmammalian vertebrates: Organizational simplicity with duplication but limited divergence in fish

Rotwein

2018

Journal of Biological Chemistry

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“…The focus of our study were patients of age 60 years or older with chronic disease conditions as they were more likely to be taking multiple medications for the long term. Increased complexity of the medication schedule and longer duration of the medication regimen represented risk factors to adherence [11]. …”

Section: Introductionmentioning

confidence: 99%

How much do elders with chronic conditions know about their medications?

Chan

Wong

et al. 2013

BMC Geriatr

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BackgroundPatients with chronic diseases often undertake multiple medication regimes to manage their condition, prevent complications and to maintain their quality of life. A patient’s medication knowledge has been defined as the awareness of drug name, purpose, administration schedule, adverse effects or side-effects and special administration instructions. Poor medication knowledge can have a negative impact on medication adherence and patient safety and, in increasing the use of medical resources. The objective of the study is to assess the medication knowledge of elderly patients with chronic disease conditions and the factors affecting this knowledge.MethodsA cross-sectional survey was conducted in patients aged ≥60 with chronic disease conditions or their caregivers were recruited from two general outpatient clinics and two medical outpatient clinics in the public sector. Participants were approached by trained interviewers to complete a semi-structured questionnaire to assess their understanding of the instructions and information relating to their regular medications, which included medication name, regimen, purpose and common side-effects and precautions.ResultsA total of 412 patients were recruited with the mean age of 72.86 ± 7.70. Of those, 221 (54.2%) were male and 226 (55.4%) were of primary school educational level or below. The mean number of medications taken per patient was 3.75 ± 1.93. Overall, 52.7% of patients felt that healthcare staff or clinic pharmacists had very clearly explained the administration instruction of the prescribed medications whilst 47.9% had very clear explanations of drug purpose but only 11.4% felt they had very clear explanations of side-effects. 396 patients (96.1%) failed to recall any side effects or precautions of each of their prescribed medications, although 232 patients (58.4%) would consult a doctor if they encountered problems with their medications. Logistic regression analysis showed that for every additional medication prescribed, the likeliness of patients to recall side-effects of all the medications prescribed was significantly lowered by 35% (OR = 0.65; 95% CI = 0.44-0.94; P = 0.023). In addition, those who finished secondary school or higher education were likely to possess more knowledge of side-effects (OR = 9.88; 95% CI = 2.11-46.25; P = 0.004).ConclusionsPatients who take medications for their chronic diseases generally lack knowledge on side-effects of their medications which could potentially affect medication compliance and medication safety.

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“…The diverse mRNA expression of growth hormone (GH) and IGF-I in breast muscle of 35-day-old Japanese quails identified in different glycerol levels (0, 4, and 8% dietary glycerol instead of corn) (Gasparino et al, 2012). Similarly the expression of mRNA IGF-I, IGF-II, and type I and II IGF receptors (IGF-IR and IGF-IIR) in breast, leg and myocardium during an early postnatal development growth stage of duck at 1-8 weeks of post hatch period (Song et al, (2013) which indicating the expression of these 4 genes differed in proliferation and differentiation of muscle tissues. IGFs in fish promote myogenic cell proliferation, differentiation and synthesis of protein (Fuentes et al, 2013).…”

Section: Effect Of Growth Factors (Gfs) In Myogenesismentioning

confidence: 99%

Skeletal muscle development in vertebrate animals

Shahjahan

2015

Asian J. Med. Biol. Res

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This review covers the pre-and post-natal development of skeletal muscle of vertebrate animals with cellular and molecular levels. The formation of skeletal muscle initiates from paraxial mesoderm during embryogenesis of individuals which develops somites and subsequently forms dermomyotome derived myotome to give rise axial musculature. This process (myogenesis) includes stem and progenitor cell maintenance, lineage specification, and terminal differentiation to form myofibrils consequent muscle fibers which control muscle mass and its multiplication. The main factors of muscle growth are proliferation and differentiation of myogenic cells in prenatal stage and also the growth of satellite cells at postnatal stage. There is no net increase in the number of muscle fibers in vertebrate animals after hatch or birth except fish. The development of muscle is characterized by hyperplasia and hypertrophy in prenatal and postnatal stages of individuals, respectively, through Wnt signalling pathway including environment, nutrition, sex, feed, growth and myogenic regulatory factors. Therefore further studies could elucidate new growth related genes, markers and factors to enhance meat production and enrich knowledge on muscle growth.

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Expression profile of insulin-like growth factor system genes in muscle tissues during the postnatal development growth stage in ducks

Cited by 6 publications

References 46 publications

The insulin-like growth factor 2 gene and locus in nonmammalian vertebrates: Organizational simplicity with duplication but limited divergence in fish

The insulin-like growth factor 2 gene and locus in nonmammalian vertebrates: Organizational simplicity with duplication but limited divergence in fish

How much do elders with chronic conditions know about their medications?

Skeletal muscle development in vertebrate animals

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