“…Among the glycolytic and pentose phosphate pathways, the phosphorylation of glucose, catalyzed by hexokinase (HK), plays a critical role and has received special attention in the literature. The predominant HK in RBCs is type-I (Murakami et al, 2002); it is present in multiple molecular forms (Bianchi et al, 1998). One isoform, HK Ib (Bianchi et al, 1998) or HKr (Murakami et al, 2002) is unique to young RBCs with rapid decay of its activity (Murakami et al, 2002).…”